Annotation Detail for PHF10

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Basic Information Top

Gene Symbol:	PHF10 ( BAF45A,FLJ10975,MGC111009,XAP135 )
Gene Full Name:	PHD finger protein 10
Band:	6q27
Quick Links	Entrez ID:55274; OMIM: 613069; Uniprot ID:PHF10_HUMAN; ENSEMBL ID: ENSG00000130024; HGNC ID: 18250
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:5 results
Experimental PTM Sites from dbPTM:4 results
Predicted PTM Sites by profile HMM from dbPTM:18 results

Location(AA)	Modification
270	Phosphoserine.
297	Phosphoserine.
301	Phosphoserine.
327	Phosphoserine.
331	Phosphoserine.

Location(AA)	Modification	Resource
19	Phosphotyrosine(EGFR)	HMM predict
92	Sulfotyrosine	HMM predict
177	Phosphotyrosine(Syk)	HMM predict
235	Phosphoserine(CK1)	HMM predict
235	Phosphoserine(ATM)	HMM predict
239	O-linked	HMM predict
243	Phosphoserine(IKK)	HMM predict
243	Phosphoserine(ATM)	HMM predict
247	Phosphoserine(ATM)	HMM predict
247	Phosphoserine	HMM predict
264	Phosphothreonine(CDC2)	HMM predict
264	Phosphothreonine(MAPK)	HMM predict
295	S-palmitoyl	HMM predict
301	Phosphoserine(PKG)	HMM predict
390	S-palmitoyl	HMM predict
395	Proline	HMM predict
396	Phosphothreonine(CDC2)	HMM predict
396	Phosphothreonine(MAPK)	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_018288
Location:chr6 169845928-169865908
strand:-

Upstream the gene:9 results
Downstream the gene:0 results
Inside the gene:7 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	169866747	169867096	349	1013
H3ac	HepG2	E	169867247	169867728	481	1579
PHF8	293T	GSE20725	169865820	169867355	1535	679
PHF8	HeLa	GSE20725	169865271	169867381	2110	418
Rb	Growing	GSE19898	169866747	169866886	139	908
Rb	Growing	GSE19898	169869989	169870121	132	4147
Rb	Quiescent	GSE19898	169867186	169867539	353	1454
TAF	k562	GSE8489	169867211	169867728	517	1561
hScc1	Bcell	GSE12603	169866747	169867048	301	989

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	169865606	169865895	289	0
ER	MCF7	GSE19013	169865593	169866098	505	0
GABP	k562	GSE8489	169848198	169849729	1531	0
H3K4me3	colorectal	cancer	169864560	169865177	617	0
H3ac	HepG2	E	169864666	169865328	662	0
hScc1	Bcell	GSE12603	169865533	169865895	362	0
hScc1	G2	GSE9613	169865606	169865895	289	0

Validated miRNA targets

miR Walk:6 results
Tarbase V5.0:0 results

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-miR-124	hsa-mir-124-1	8	19561591
hsa-miR-124	hsa-mir-124-2	8	19561591
hsa-miR-124	hsa-mir-124-3	20	19561591
hsa-miR-9*	hsa-mir-9-1	1	19561591
hsa-miR-9*	hsa-mir-9-2	5	19561591
hsa-miR-9*	hsa-mir-9-3	15	19561591

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
23501	mRNA	PHF10	chr6	169919888	169924033	479	mRNA	PHF10	chr6	169921635	169941616	Sense/Antisense (SA) pairs

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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