AutismKB 2.0

Annotation Detail for PPP2R5D


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Basic Information Top
Gene Symbol:PPP2R5D ( B56D,MGC2134,MGC8949 )
Gene Full Name: protein phosphatase 2, regulatory subunit B', delta
Band: 6p21.1
Quick LinksEntrez ID:5528; OMIM: 601646; Uniprot ID:2A5D_HUMAN; ENSEMBL ID: ENSG00000112640; HGNC ID: 9312
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
530SH3-binding; class I (Potential).
553Phosphothreonine.
565Nuclear localization signal (Potential).
573Phosphoserine.
598Phosphoserine.
Location(AA) Modifications Resource
598Phosphoserine.Swiss-Prot 53.0
598PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
24Phosphoserine(ATM)HMM predict
50Phosphoserine(IKK)HMM predict
50Phosphoserine(ATM)HMM predict
61N-linkedHMM predict
62O-linkedHMM predict
63O-linkedHMM predict
63Phosphothreonine(CDC2)HMM predict
88Phosphoserine(PKG)HMM predict
89Phosphoserine(PKB)HMM predict
168Phosphotyrosine(EGFR)HMM predict
188N-linkedHMM predict
356Phosphoserine(IKK)HMM predict
356Phosphoserine(CK1)HMM predict
374Phosphoserine(IKK)HMM predict
459N-linkedHMM predict
538Phosphothreonine(MAPK)HMM predict
573Phosphoserine(PKG)HMM predict
598Phosphoserine(ATM)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006245
  • Location:chr6 43060307-43088055
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 43059745 43060582 837 144
H3ac HepG2E 43059610 43059991 381 507
PHF8 HeLaGSE20725 43059452 43060724 1272 220
Rb QuiescentGSE19898 43060024 43060301 277 145
Rb SenescentGSE19898 43059713 43060308 595 297
TAF k562GSE8489 43059457 43059674 217 742
p130 shRbSenescentGSE19898 43059965 43060135 170 258
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 43084819 43085131 312 0
CTCF CD4SISSRdata 43084819 43085131 312 0
CTCF HelaGSE12889 43084825 43085095 270 0
CTCF G2GSE9613 43060074 43060714 640 0
CTCF G2GSE9613 43084391 43085290 899 0
CTCF G2GSE9613 43085810 43086356 546 0
CTCF G2GSE9613 43086876 43087178 302 0
H3K4me3 colorectalcancer 43060999 43061444 445 0
H3ac HepG2E 43060855 43061444 589 0
H3ac HepG2E 43061798 43063123 1325 0
hScc1 BcellGSE12603 43059845 43060963 1118 0
hScc1 BcellGSE12603 43084899 43085069 170 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
22614 mRNA PPP2R5D chr6 43060307 43088056 110 mRNA MEA chr6 43087946 43089596Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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