AutismKB 2.0

Annotation Detail for PPP4C


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Basic Information Top
Gene Symbol:PPP4C ( PP4,PP4C,PPH3,PPP4,PPX )
Gene Full Name: protein phosphatase 4, catalytic subunit
Band: 16p11.2
Quick LinksEntrez ID:5531; OMIM: 602035; Uniprot ID:PP4C_HUMAN; ENSEMBL ID: ENSG00000149923; HGNC ID: 9319
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
307Leucine methyl ester (By similarity).
Location(AA) Modifications Resource
307Leucine methyl ester (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
47Phosphoserine(CDC2)HMM predict
77Phosphotyrosine(SRC)HMM predict
179Phosphothreonine(PKC)HMM predict
209Phosphoserine(CDC2)HMM predict
250N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002720
  • Location:chr16 29994884-30004188
  • strand:+
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
GABP k562GSE8489 29995307 29997891 2584 0
H3K4me3 colorectalcancer 29995493 29996212 719 0
H3ac HepG2E 29995423 29997891 2468 0
NRSF mAbJurkat 29999637 29999974 337 0
TAF HelaGSE8489 30000923 30001143 220 0
TFAP2C MCF7GSE21234 29995208 29995698 490 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018