AutismKB 2.0

Annotation Detail for LAPTM4B


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Basic Information Top
Gene Symbol:LAPTM4B ( LAPTM4beta,LC27 )
Gene Full Name: lysosomal protein transmembrane 4 beta
Band: 8q22.1
Quick LinksEntrez ID:55353; OMIM: 613296; Uniprot ID:LAP4B_HUMAN; ENSEMBL ID: ENSG00000104341; HGNC ID: 13646
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
367Phosphotyrosine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
55Phosphothreonine(PKC)HMM predict
61Phosphothreonine(PKA)HMM predict
64Phosphoserine(CDC2)HMM predict
115Phosphoserine(PKG)HMM predict
120MethylarginineHMM predict
129Phosphothreonine(PKC)HMM predict
163S-palmitoylHMM predict
198N-linkedHMM predict
294N-linkedHMM predict
331N-linkedHMM predict
342N-linkedHMM predict
345O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_018407
  • Location:chr8 98856984-98934004
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 98845702 98845948 246 11160
ER MCF7GSE19013 98844894 98846315 1421 11380
ER MCF7GSE10800 98845702 98846322 620 10973
FOXA1 MCF7GSE15244 98856425 98856606 181 469
H3K4me3 colorectalcancer 98856425 98856606 181 469
Nanog hESGSE18292 98843057 98843459 402 13727
Oct1 HelaGSE14283 98838438 98838483 45 18524
RARA MCF7GSE15244 98844978 98845311 333 11840
RARA MCF7GSE15244 98845702 98846257 555 11005
RARA MCF7GSE15244 98856425 98856606 181 469
RARG MCF7GSE15244 98856425 98856606 181 469
STAT1 HeLaGSE12782 98843426 98846369 2943 12087
STAT1 HeLaGSE12783 98843418 98846329 2911 12111
USF1 HepG2E 98856425 98856606 181 469
p63 keratinocytesGSE17611 98836539 98837471 932 19980
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 98934785 98935596 811 1186
RARA MCF7GSE15244 98935028 98935665 637 1342
RARG MCF7GSE15244 98934992 98935596 604 1290
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 98903419 98903667 248 0
CTCF CD4SISSRdata 98903419 98903667 248 0
CTCF HelaGSE12889 98903478 98903722 244 0
CTCF JurkatGSE12889 98903499 98903780 281 0
CTCF G2GSE9613 98857108 98857537 429 0
CTCF G2GSE9613 98880045 98880180 135 0
CTCF G2GSE9613 98903363 98903552 189 0
CTCF G2GSE9613 98931232 98931523 291 0
FOXA1 MCF7GSE15244 98856964 98857108 144 0
FOXA1 MCF7GSE15244 98858940 98859428 488 0
FOXA1 MCF7GSE15244 98867336 98867504 168 0
FOXA1 MCF7GSE15244 98920913 98921131 218 0
FOXA1 MCF7GSE15244 98923043 98923431 388 0
FoxA1 MCF7MACSdata 98869482 98869662 180 0
GATA3 MCF7GSE15244 98919374 98920563 1189 0
GATA3 MCF7GSE15244 98920913 98921207 294 0
H3K4me2 HCT116GSE10453 98858034 98858503 469 0
H3ac HepG2E 98857963 98858503 540 0
Myc hESGSE17917 98857638 98857933 295 0
Oct1 H2O2-HelaGSE14283 98858073 98858104 31 0
Oct1 HelaGSE14283 98858072 98858103 31 0
Oct1 HelaGSE14283 98864980 98865006 26 0
Oct1 HelaGSE14283 98916672 98916732 60 0
Oct4 hESGSE21916 98864793 98865314 521 0
P300 T30-glioblastomaGSE21026 98916532 98917272 740 0
RARA MCF7GSE15244 98859046 98859666 620 0
RARA MCF7GSE15244 98916401 98917170 769 0
RARA MCF7GSE15244 98920913 98921207 294 0
RARG MCF7GSE15244 98916508 98917170 662 0
STAT1 HeLaGSE12782 98882913 98884444 1531 0
STAT1 HeLaGSE12783 98882721 98884410 1689 0
STAT1 IFNSISSRdata 98883358 98884341 983 0
Sox2 hESGSE18292 98866969 98867294 325 0
TAF HelaGSE8489 98857674 98858503 829 0
TAF k562GSE8489 98857927 98858503 576 0
USF1 HepG2E 98856964 98857194 230 0
USF1 HepG2E 98857889 98858503 614 0
USF2 HepG2E 98856964 98857194 230 0
hScc1 BcellGSE12603 98857263 98857674 411 0
hScc1 BcellGSE12603 98903363 98903797 434 0
hScc1 CdLSGSE12603 98903363 98904078 715 0
hScc1 CdLSGSE12603 98921131 98921819 688 0
p130 SenescentGSE19898 98857686 98858142 456 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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