AutismKB 2.0

Annotation Detail for LGR4


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:LGR4 ( GPR48 )
Gene Full Name: leucine-rich repeat-containing G protein-coupled receptor 4
Band: 11p14.1
Quick LinksEntrez ID:55366; OMIM: 606666; Uniprot ID:LGR4_HUMAN; ENSEMBL ID: ENSG00000205213; HGNC ID: 13299
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
68N-linked (GlcNAc...) (Potential).
199N-linked (GlcNAc...) (Potential).
294N-linked (GlcNAc...) (Potential).
314N-linked (GlcNAc...) (Potential).
505N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
68N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
199N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
294N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
314N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
505N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
22O-linkedHMM predict
68N-linkedHMM predict
164Phosphoserine(CK1)HMM predict
249Phosphoserine(PKG)HMM predict
307Phosphoserine(PKB)HMM predict
314N-linkedHMM predict
323O-linkedHMM predict
505N-linkedHMM predict
566O-linkedHMM predict
568O-linkedHMM predict
569Phosphoserine(CK1)HMM predict
569Phosphoserine(IKK)HMM predict
701Phosphothreonine(CDK)HMM predict
703O-linkedHMM predict
738Phosphoserine(CK1)HMM predict
738Phosphoserine(CK2)HMM predict
741Phosphoserine(IKK)HMM predict
741Phosphoserine(ATM)HMM predict
778Phosphoserine(ATM)HMM predict
820Phosphothreonine(PKC)HMM predict
820Phosphothreonine(PKA)HMM predict
827Phosphoserine(IKK)HMM predict
829Phosphoserine(IKK)HMM predict
842Phosphotyrosine(Syk)HMM predict
843SulfotyrosineHMM predict
854N-linkedHMM predict
880Phosphoserine(IKK)HMM predict
906Phosphoserine(CK1)HMM predict
908Phosphotyrosine(Syk)HMM predict
908SulfotyrosineHMM predict
908Phosphotyrosine(INSR)HMM predict
917Phosphoserine(CK2)HMM predict
935ArginineHMM predict
941ArginineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_018490
  • Location:chr11 27344085-27450868
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 27450762 27451327 565 176
H3ac HepG2E 27451216 27451788 572 634
Nanog hESGSE18292 27461418 27461711 293 10696
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 DLD1GSE12801 27373525 27374375 850 0
FOXA1 DLD1GSE12801 27379548 27380146 598 0
FOXA1 DLD1GSE12801 27442441 27442976 535 0
FOXA1 MCF7GSE15244 27346184 27346701 517 0
FOXA1 MCF7GSE15244 27379728 27380146 418 0
FOXA1 MCF7GSE15244 27394323 27395389 1066 0
FOXA1 MCF7GSE15244 27407665 27407919 254 0
FoxA1 MCF7MACSdata 27379821 27380088 267 0
FoxA1 MCF7MACSdata 27395006 27395259 253 0
GATA3 MCF7GSE15244 27394072 27394923 851 0
H3K4me3 colorectalcancer 27448598 27449674 1076 0
H3ac HepG2E 27374885 27375594 709 0
H3ac HepG2E 27376476 27376982 506 0
H3ac HepG2E 27445874 27449674 3800 0
Myc K562GSE19551 27376160 27376516 356 0
RARA MCF7GSE15244 27346147 27346883 736 0
RARA MCF7GSE15244 27394566 27395143 577 0
RARG MCF7GSE15244 27379891 27380146 255 0
RARG MCF7GSE15244 27394566 27395037 471 0
Rb GrowingGSE19898 27373753 27373981 228 0
Rb QuiescentGSE19898 27371061 27371158 97 0
TFAP2C MCF7GSE21234 27345936 27346406 470 0
TFAP2C MCF7GSE21234 27401303 27401692 389 0
TFAP2C MCF7GSE21234 27407866 27408231 365 0
TFAP2C MCF7GSE21234 27442396 27442914 518 0
hScc1 BcellGSE12603 27449937 27450762 825 0
hScc1 CdLSGSE12603 27419825 27420136 311 0
hScc1 CdLSGSE12603 27449937 27450887 950 0
hScc1 G2GSE9613 27448960 27450644 1684 0
p130 shRbQuiescentGSE19898 27348642 27348903 261 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
4249 EST chr11 27449853 27451583 1016 mRNA LGR4 chr11 27344085 27450869 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved