AutismKB 2.0

Annotation Detail for HES6


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Basic Information Top
Gene Symbol:HES6 ( HES-6,bHLHb41,bHLHc23 )
Gene Full Name: hairy and enhancer of split 6 (Drosophila)
Band: 2q37.3
Quick LinksEntrez ID:55502; OMIM: 610331; Uniprot ID:HES6_HUMAN; ENSEMBL ID: ENSG00000144485; HGNC ID: 18254
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
224WRPW motif.
Location(AA) Modifications Resource
Location(AA) Modification Resource
169O-linkedHMM predict
173O-linkedHMM predict
173Phosphoserine(CDC2)HMM predict
194Phosphoserine(ATM)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_018645
  • Location:chr2 238811648-238813408
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 238813065 238815062 1997 655
Fos K562GSE19551 238813342 238813837 495 181
Myc hESGSE17917 238814276 238814631 355 1045
PHF8 HeLaGSE20725 238812788 238814248 1460 110
hScc1 BcellGSE12603 238813875 238814937 1062 998
hScc1 G2GSE9613 238812032 238814937 2905 76
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 238799731 238800378 647 11594
CTCF G2GSE9613 238800805 238800986 181 10753
CTCF G2GSE9613 238805111 238805418 307 6384
CTCF G2GSE9613 238807985 238808181 196 3566
CTCF G2GSE9613 238808830 238809049 219 2709
CTCF G2GSE9613 238809945 238810221 276 1566
ETS1 JurkatGSE17954 238807356 238808210 854 3866
Myc K562GSE19551 238804792 238805193 401 6656
TAF k562GSE8489 238803771 238803979 208 7774
TAF k562GSE8489 238808723 238809257 534 2659
TFAP2C MCF7GSE21234 238800532 238800959 427 10903
hScc1 G2GSE9613 238807950 238808181 231 3583
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 238812032 238812480 448 0
PHF8 293TGSE20725 238812799 238813771 972 0
hScc1 BcellGSE12603 238812789 238813570 781 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018