AutismKB 2.0

Annotation Detail for SMPD3


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Basic Information Top
Gene Symbol:SMPD3 ( FLJ22593,MGC138443,NSMASE2 )
Gene Full Name: sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
Band: 16q22.1
Quick LinksEntrez ID:55512; OMIM: 605777; Uniprot ID:NSMA2_HUMAN; ENSEMBL ID: ENSG00000103056; HGNC ID: 14240
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
86Phosphoserine(IKK)HMM predict
177O-linkedHMM predict
180O-linkedHMM predict
183O-linkedHMM predict
186Phosphoserine(IKK)HMM predict
189Phosphoserine(CDC2)HMM predict
237Phosphoserine(CK2)HMM predict
276MethylarginineHMM predict
279Phosphothreonine(CDK)HMM predict
279Phosphothreonine(MAPK)HMM predict
279Phosphothreonine(CDC2)HMM predict
291Phosphoserine(IKK)HMM predict
294Phosphoserine(IKK)HMM predict
294Phosphoserine(CDC2)HMM predict
296O-linkedHMM predict
298O-linkedHMM predict
314O-linkedHMM predict
394S-palmitoylHMM predict
398S-palmitoylHMM predict
490Phosphothreonine(PKC)HMM predict
490Phosphothreonine(PKA)HMM predict
491Phosphoserine(CK2)HMM predict
492Phosphoserine(CK1)HMM predict
493Phosphoserine(CDC2)HMM predict
515N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_018667
  • Location:chr16 66949732-67039904
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 67039726 67040693 967 305
NRSF mAbJurkat 67040000 67041094 1094 643
NRSF mAbJurkat 67041644 67041808 164 1822
NRSF mAbJurkat 67042125 67042835 710 2576
NRSF mAbJurkat 67043755 67045839 2084 4893
NRSF mAbJurkat 67047186 67047675 489 7526
NRSF pAbJurkat 67042528 67042835 307 2777
P300 T0-glioblastomaGSE21026 67039720 67040480 760 196
P300 T30-glioblastomaGSE21026 67039473 67040501 1028 83
Rb QuiescentGSE19898 67039867 67040013 146 36
VDR GM10861-UnstimGSE22484 67039394 67040658 1264 122
VDR GM10861-stimGSE22484 67039527 67040736 1209 227
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 66987975 66988314 339 0
CTCF CD4SISSRdata 66987975 66988314 339 0
CTCF G2GSE9613 66951973 66952191 218 0
CTCF G2GSE9613 66963190 66963521 331 0
CTCF G2GSE9613 66964160 66964327 167 0
CTCF G2GSE9613 66965905 66966039 134 0
CTCF G2GSE9613 66973446 66974055 609 0
CTCF G2GSE9613 66980540 66980864 324 0
CTCF G2GSE9613 66987923 66988290 367 0
CTCF G2GSE9613 67036602 67037248 646 0
ER MCF7GSE19013 67007705 67008448 743 0
ER MCF7GSE19013 67017561 67018141 580 0
FOXA1 MCF7GSE15244 66997949 66998606 657 0
FOXA1 MCF7GSE15244 67007336 67008384 1048 0
FOXA1 MCF7GSE15244 67008721 67009619 898 0
Fos K562GSE19551 66972664 66973303 639 0
FoxA1 MCF7MACSdata 67007815 67008170 355 0
Myc K562GSE19551 67028086 67028384 298 0
NFkBII GM10847GSE19485 66959504 66961955 2451 0
NRSF JurkatGSE13047 67034961 67036302 1341 0
NRSF JurkatGSE13047 67039230 67040545 1315 0
NRSF mAbJurkat 67029678 67030217 539 0
NRSF mAbJurkat 67030670 67031566 896 0
NRSF mAbJurkat 67033752 67038247 4495 0
NRSF mAbJurkat 67039207 67039734 527 0
NRSF-mono JurkatQuESTdata 67035172 67036068 896 0
NRSF-mono JurkatQuESTdata 67039185 67040589 1404 0
NRSF pAbJurkat 67033965 67038280 4315 0
NRSF-poly JurkatQuESTdata 67035255 67036029 774 0
NRSF-poly JurkatQuESTdata 67038560 67040660 2100 0
Oct1 H2O2-HelaGSE14283 66990891 66990920 29 0
RARA MCF7GSE15244 66997870 66998642 772 0
RARA MCF7GSE15244 67007260 67008272 1012 0
RARA MCF7GSE15244 67017223 67018184 961 0
USF1 HepG2E 66972358 66972860 502 0
hScc1 BcellGSE12603 66956187 66957317 1130 0
hScc1 BcellGSE12603 66958877 66959093 216 0
hScc1 BcellGSE12603 66970557 66971065 508 0
hScc1 BcellGSE12603 66987815 66988313 498 0
hScc1 BcellGSE12603 67036707 67037677 970 0
hScc1 BcellGSE12603 67038320 67038892 572 0
hScc1 BcellGSE12603 67039544 67039869 325 0
hScc1 CdLSGSE12603 66987852 66988290 438 0
hScc1 CdLSGSE12603 67036671 67037506 835 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
10151 mRNA PRMT7 chr16 66915386 66949967 235 mRNA SMPD3 chr16 66949732 67039905Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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