Annotation Detail for DHTKD1

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Basic Information Top

Gene Symbol:	DHTKD1 ( DKFZp762M115,KIAA1630,MGC3090 )
Gene Full Name:	dehydrogenase E1 and transketolase domain containing 1
Band:	10p14
Quick Links	Entrez ID:55526; OMIM: NA; Uniprot ID:DHTK1_HUMAN; ENSEMBL ID: ENSG00000181192; HGNC ID: 23537
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_018706
Location:chr10 12150976-12205228
strand:+

Upstream the gene:8 results
Downstream the gene:0 results
Inside the gene:8 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
Fos	K562	GSE19551	12150455	12151196	741	151
Gata1	K562	GSE18868	12145363	12145899	536	5346
Gata2	K562	GSE18868	12145296	12145878	582	5390
Myc	K562	GSE19551	12145378	12145776	398	5400
PHF8	293T	GSE20725	12150214	12151548	1334	96
TAF	Hela	GSE8489	12149484	12149700	216	1385
TFAP2C	MCF7	GSE21234	12150518	12150918	400	259
p130	Senescent	GSE19898	12150560	12150970	410	212

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
H3ac	HepG2	E	12151245	12151466	221	0
NFkBII	GM12878	GSE19485	12203248	12205651	2403	0
NFkBII	GM12892	GSE19485	12203357	12205418	2061	0
NFkBII	GM18526	GSE19485	12203411	12205472	2061	0
PHF8	HeLa	GSE20725	12150508	12151531	1023	0
Rb	Quiescent	GSE19898	12150914	12151123	209	0
TFAP2C	MCF7	GSE21234	12150921	12151145	224	0
hScc1	CdLS	GSE12603	12150504	12151466	962	0

Validated miRNA targets

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
12957	HTC	DHTKD1	chr19	21561435	21683332	175	EST		chr19	21568306	21569242	Sense/Antisense (SA) pairs

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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