Annotation Detail for PRIM1

View Evidences	View Variants	View Annotations

Basic Information Top

Gene Symbol:	PRIM1 ( MGC12308,p49 )
Gene Full Name:	primase, DNA, polypeptide 1 (49kDa)
Band:	12q13.3
Quick Links	Entrez ID:5557; OMIM: 176635; Uniprot ID:PRI1_HUMAN; ENSEMBL ID: ENSG00000198056; HGNC ID: 9369
Relate to Another Database:	SFARIGene; denovo-db

Post Translation Modification

Location(AA)	Modification
1	N-acetylmethionine.
131	Zinc knuckle motif.

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	55437568	55437827	259	5285
CTCF	CD4	SISSRdata	55437568	55437827	259	5285
CTCF	G2	GSE9613	55437711	55437952	241	5419
hScc1	Bcell	GSE12603	55437711	55438023	312	5455

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
ETS1	Jurkat	GSE17954	55431572	55432815	1243
H3ac	HepG2	E	55430028	55430453	425
H3ac	HepG2	E	55430825	55431332	507
H3ac	HepG2	E	55431641	55432114	473
Oct1	H2O2-Hela	GSE14283	55428680	55428720	40
Oct1	Hela	GSE14283	55428681	55428720	39
Rb	Growing	GSE19898	55432057	55432466	409
Rb	Quiescent	GSE19898	55431916	55432632	716
Rb	Senescent	GSE19898	55431858	55432627	769
Rb	shRbQuiescent	GSE19898	55432101	55432557	456
Rb	shRbSenescence	GSE19898	55431976	55432534	558
TAF	Hela	GSE8489	55430100	55430453	353
p130	Quiescent	GSE19898	55432105	55432502	397
p130	Senescent	GSE19898	55432083	55432552	469
p130	shRbSenescent	GSE19898	55431980	55432650	670

Validated miRNA targets

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-let-7b	hsa-let-7b	22	18668040
hsa-let-7b*	hsa-let-7b	22	18668040
hsa-miR-1	hsa-mir-1-2	18	18668040
hsa-miR-1	hsa-mir-1-1	20	18668040
hsa-miR-155	hsa-mir-155	21	18668040
hsa-miR-155*	hsa-mir-155	21	18668040
hsa-miR-15a	hsa-mir-15a	13	18362358
hsa-miR-15a*	hsa-mir-15a	13	18362358
hsa-miR-16	hsa-mir-16-1	13	18362358
hsa-miR-16	hsa-mir-16-2	3	18362358
hsa-miR-16	hsa-mir-16-1	13	18668040
hsa-miR-16	hsa-mir-16-2	3	18668040
hsa-miR-16-1*	hsa-mir-16-1	13	18362358
hsa-miR-30a	hsa-mir-30a	6	18668040
hsa-miR-30a*	hsa-mir-30a	6	18668040
hsa-miR-30b	hsa-mir-30b	8	18668040
hsa-miR-30b*	hsa-mir-30b	8	18668040
hsa-miR-30c	hsa-mir-30c-2	6	18668040
hsa-miR-30c	hsa-mir-30c-1	1	18668040
hsa-miR-30c-1*	hsa-mir-30c-1	1	18668040
hsa-miR-30c-2*	hsa-mir-30c-2	6	18668040
hsa-miR-30d	hsa-mir-30d	8	18668040
hsa-miR-30d*	hsa-mir-30d	8	18668040
hsa-miR-30e	hsa-mir-30e	1	18668040
hsa-miR-30e*	hsa-mir-30e	1	18668040

ID in Tarbase	Data Type	Support Type	miRNA	Gene	Direct Support	Publication
884	Unknown	pSILAC	let-7b	PRIM1	down 50-25%	18668040
Ensembl	Protein Type	Differentially expressed in	Pathology or Event	Mis Regulation	Gene Expression	Tumour Involvement
ENSG00000198056		n_a	n_a	n_a	lymphocyte	"benign tumour, malignant tumour, carcinoma, leukaemia"

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
6149	EST		chr12	55432211	55446324	123	mRNA	PRIM1	chr12	55411632	55432413	Sense/Antisense (SA) pairs

Simple Query:

Paper Collected: 6/30/2018

Last Update: 8/26/2018