AutismKB 2.0

Annotation Detail for TRMT1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:TRMT1 ( FLJ20244,TRM1 )
Gene Full Name: TRM1 tRNA methyltransferase 1 homolog (S. cerevisiae)
Band: 19p13.13
Quick LinksEntrez ID:55621; OMIM: 611669; Uniprot ID:TRM1_HUMAN; ENSEMBL ID: ENSG00000104907; HGNC ID: 25980
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
120Phosphoserine (By similarity).
625Phosphoserine.
628Phosphothreonine.
646Phosphothreonine.
Location(AA) Modifications Resource
646Phosphothreonine.Swiss-Prot 53.0
Location(AA) Modification Resource
39N-linkedHMM predict
235Phosphotyrosine(INSR)HMM predict
338Phosphoserine(PKG)HMM predict
381Phosphothreonine(MAPK)HMM predict
381Phosphothreonine(CDC2)HMM predict
452Phosphoserine(CK1)HMM predict
514Phosphoserine(CK1)HMM predict
532N-linkedHMM predict
540N-linkedHMM predict
628Phosphothreonine(MAPK)HMM predict
644N-linkedHMM predict
646Phosphothreonine(CDC2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_017722
  • Location:chr19 13076715-13088331
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 13087846 13089191 1345 187
P300 T0-glioblastomaGSE21026 13088030 13089040 1010 204
P300 T30-glioblastomaGSE21026 13087956 13089190 1234 242
PHF8 293TGSE20725 13088002 13088840 838 90
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 13076384 13076732 348 158
CTCF CD4SISSRdata 13076384 13076732 348 158
hScc1 BcellGSE12603 13076375 13076696 321 180
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 13087826 13088657 831 0
H3ac HepG2E 13086877 13088036 1159 0
USF1 HepG2E 13086877 13088657 1780 0
hScc1 BcellGSE12603 13087962 13088400 438 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7b hsa-let-7b 22 18668040
hsa-let-7b* hsa-let-7b 22 18668040
hsa-miR-1 hsa-mir-1-2 18 18668040
hsa-miR-1 hsa-mir-1-1 20 18668040
hsa-miR-155 hsa-mir-155 21 18668040
hsa-miR-155* hsa-mir-155 21 18668040
hsa-miR-16 hsa-mir-16-1 13 18668040
hsa-miR-16 hsa-mir-16-2 3 18668040
hsa-miR-30a hsa-mir-30a 6 18668040
hsa-miR-30a* hsa-mir-30a 6 18668040
hsa-miR-30b hsa-mir-30b 8 18668040
hsa-miR-30b* hsa-mir-30b 8 18668040
hsa-miR-30c hsa-mir-30c-2 6 18668040
hsa-miR-30c hsa-mir-30c-1 1 18668040
hsa-miR-30c-1* hsa-mir-30c-1 1 18668040
hsa-miR-30c-2* hsa-mir-30c-2 6 18668040
hsa-miR-30d hsa-mir-30d 8 18668040
hsa-miR-30d* hsa-mir-30d 8 18668040
hsa-miR-30e hsa-mir-30e 1 18668040
hsa-miR-30e* hsa-mir-30e 1 18668040
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
904 Unknown pSILAC let-7b TRMT1 down 50-25% 18668040
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000104907 n_a n_a n_a "epithelium, lymphoblast, lymphocyte" "benign tumour, malignant tumour, carcinoma, leukaemia, non-Hodgkin's, sarcoma"
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018