AutismKB 2.0

Annotation Detail for DEPDC1


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Basic Information Top
Gene Symbol:DEPDC1 ( DEP.8,DEPDC1-V2,DEPDC1A,FLJ20354,SDP35 )
Gene Full Name: DEP domain containing 1
Band: 1p31.3
Quick LinksEntrez ID:55635; OMIM: 612002; Uniprot ID:DEP1A_HUMAN; ENSEMBL ID: ENSG00000024526; HGNC ID: 22949
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
512Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
59N-linkedHMM predict
60N-linkedHMM predict
62N-linkedHMM predict
110Phosphoserine(CDK)HMM predict
110Phosphoserine(CDC2)HMM predict
114Phosphothreonine(PKC)HMM predict
129N-linkedHMM predict
147Phosphothreonine(CDC2)HMM predict
156Phosphoserine(ATM)HMM predict
182Phosphoserine(CK1)HMM predict
227N-linkedHMM predict
238N-linkedHMM predict
265N-linkedHMM predict
268Phosphotyrosine(EGFR)HMM predict
359Phosphoserine(CK2)HMM predict
361PhosphoserineHMM predict
361Phosphoserine(CK1)HMM predict
432N-linkedHMM predict
523Phosphoserine(PKG)HMM predict
523Phosphoserine(PKB)HMM predict
606S-palmitoylHMM predict
673Phosphoserine(CAMK2)HMM predict
722N-linkedHMM predict
726N-linkedHMM predict
756Phosphotyrosine(INSR)HMM predict
756Phosphotyrosine(Syk)HMM predict
758Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_017779
  • Location:chr1 68713526-68735294
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 68735038 68735717 679 83
TAF k562GSE8489 68735472 68736733 1261 808
USF1 HepG2E 68735562 68736956 1394 965
p130 shRbQuiescentGSE19898 68734967 68735763 796 71
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Nanog ESGSE20650 68703187 68703678 491 10094
Oct1 HelaGSE14283 68701258 68701306 48 12245
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 68734645 68735472 827 0
E2F4 G0GSE7516 68734609 68735824 1215 0
E2F4 SGSE7516 68734609 68735755 1146 0
H3K4me2 HCT116GSE10453 68734609 68734899 290 0
H3K4me3 colorectalcancer 68734609 68734966 357 0
H3ac HepG2E 68734609 68735079 470 0
LIN54 G0GSE7516 68734609 68735599 990 0
LIN9 G0GSE7516 68734609 68735905 1296 0
LIN9 SGSE7516 68734609 68735941 1332 0
PHF8 293TGSE20725 68734726 68735857 1131 0
TAF k562GSE8489 68734609 68735042 433 0
USF1 HepG2E 68734609 68735255 646 0
USF2 HepG2E 68734609 68735079 470 0
p130 QuiescentGSE19898 68734760 68735575 815 0
p130 SenescentGSE19898 68734840 68735694 854 0
p130 shRbSenescentGSE19898 68734674 68735652 978 0
p130 G0GSE7516 68734609 68735976 1367 0
p130 SGSE7516 68734609 68735867 1258 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-1 hsa-mir-1-2 18 15685193
hsa-miR-1 hsa-mir-1-1 20 15685193
hsa-miR-124 hsa-mir-124-1 8 15685193
hsa-miR-124 hsa-mir-124-2 8 15685193
hsa-miR-124 hsa-mir-124-3 20 15685193
hsa-miR-373 hsa-mir-373 19 15685193
hsa-miR-373* hsa-mir-373 19 15685193
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
243 Unknown MicroArray miR-124 DEPDC1 n_a 15685193
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000024526 G1-to-S transition n_a n_a n_a n_a
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
945 EST chr1 68656832 68660688 166 mRNA DEPDC1 chr1 68652959 68674728Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018