AutismKB 2.0

Annotation Detail for CHD7


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Basic Information Top
Gene Symbol:CHD7 ( FLJ20357,FLJ20361,IS3,KAL5,KIAA1416 )
Gene Full Name: chromodomain helicase DNA binding protein 7
Band: 8q12.2
Quick LinksEntrez ID:55636; OMIM: 608765,608892; Uniprot ID:CHD7_HUMAN; ENSEMBL ID: ENSG00000171316; HGNC ID: 20626
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
1108DEAH box.
1874Phosphoserine.
2254Phosphoserine.
2255Phosphoserine.
2350Phosphothreonine.
2356Phosphoserine.
2533Phosphoserine.
2559Phosphoserine.
Location(AA) Modifications Resource
1797PhosphoserinePhospho.ELM 6.0
2559Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
62N-linkedHMM predict
72SulfotyrosineHMM predict
75Phosphotyrosine(Syk)HMM predict
100Phosphoserine(MAPK)HMM predict
103Phosphoserine(ATM)HMM predict
105Phosphotyrosine(Syk)HMM predict
175O-linkedHMM predict
175Phosphoserine(ATM)HMM predict
214Phosphoserine(ATM)HMM predict
272Phosphoserine(CDC2)HMM predict
276O-linkedHMM predict
276Phosphoserine(CDC2)HMM predict
289Phosphothreonine(PKC)HMM predict
291N-linkedHMM predict
296Phosphoserine(ATM)HMM predict
298Phosphothreonine(PKC)HMM predict
301Phosphoserine(CDC2)HMM predict
305N-linkedHMM predict
306N-linkedHMM predict
324N-linkedHMM predict
325N-linkedHMM predict
329N-linkedHMM predict
336N-linkedHMM predict
337N-linkedHMM predict
341N-linkedHMM predict
384Phosphoserine(ATM)HMM predict
389O-linkedHMM predict
390Phosphotyrosine(Abl)HMM predict
392O-linkedHMM predict
392Phosphoserine(CDC2)HMM predict
397Phosphoserine(CDC2)HMM predict
397PhosphoserineHMM predict
408O-linkedHMM predict
408O-linkedHMM predict
408Phosphothreonine(CDC2)HMM predict
408Phosphothreonine(MAPK)HMM predict
436O-linkedHMM predict
527O-linkedHMM predict
528O-linkedHMM predict
543Phosphoserine(CDC2)HMM predict
547Phosphothreonine(CDC2)HMM predict
547Phosphothreonine(MAPK)HMM predict
557Phosphoserine(CAMK2)HMM predict
586Phosphotyrosine(INSR)HMM predict
637Phosphoserine(ATM)HMM predict
670Phosphothreonine(CDC2)HMM predict
689Phosphothreonine(CDC2)HMM predict
689Phosphothreonine(MAPK)HMM predict
722Phosphoserine(CK2)HMM predict
730Phosphothreonine(CDC2)HMM predict
730Phosphothreonine(MAPK)HMM predict
730Phosphothreonine(CDK)HMM predict
734Phosphoserine(ATM)HMM predict
751Phosphoserine(PKG)HMM predict
760Phosphothreonine(PKA)HMM predict
768Phosphoserine(CK2)HMM predict
782Phosphoserine(CDC2)HMM predict
782Phosphoserine(IKK)HMM predict
784Phosphoserine(IKK)HMM predict
785N-linkedHMM predict
787Phosphoserine(CK1)HMM predict
787Phosphoserine(IKK)HMM predict
794Phosphoserine(CK2)HMM predict
817Phosphoserine(PKG)HMM predict
832N-linkedHMM predict
835Phosphotyrosine(Jak)HMM predict
870Phosphoserine(CK2)HMM predict
958Phosphoserine(CK2)HMM predict
962Phosphotyrosine(INSR)HMM predict
1171Phosphothreonine(CK2)HMM predict
1225N-linkedHMM predict
1374N-linkedHMM predict
1447N-linkedHMM predict
1450N-linkedHMM predict
1519N-linkedHMM predict
1562Phosphothreonine(PKA)HMM predict
1581Phosphoserine(CK1)HMM predict
1581Phosphoserine(CK2)HMM predict
1583Phosphoserine(CK1)HMM predict
1601Phosphotyrosine(EGFR)HMM predict
1681N-linkedHMM predict
1727Phosphotyrosine(EGFR)HMM predict
1727Phosphotyrosine(Jak)HMM predict
1766PhosphoserineHMM predict
1857Phosphotyrosine(SRC)HMM predict
1857SulfotyrosineHMM predict
1862Phosphothreonine(CDK)HMM predict
1874Phosphoserine(CDC2)HMM predict
1882PhosphoserineHMM predict
1892Phosphoserine(PKG)HMM predict
1892Phosphoserine(CAMK2)HMM predict
1905N-linkedHMM predict
1975Phosphotyrosine(Syk)HMM predict
2010Phosphoserine(CK1)HMM predict
2139N-linkedHMM predict
2144N-linkedHMM predict
2199Phosphoserine(CK2)HMM predict
2203Phosphoserine(PKG)HMM predict
2213Phosphoserine(CK1)HMM predict
2229Phosphoserine(CK1)HMM predict
2229Phosphoserine(IKK)HMM predict
2233Phosphoserine(CK1)HMM predict
2237Phosphoserine(CK2)HMM predict
2251Phosphoserine(CK1)HMM predict
2251Phosphoserine(CK2)HMM predict
2254Phosphoserine(CK2)HMM predict
2255Phosphoserine(CK1)HMM predict
2255Phosphoserine(ATM)HMM predict
2272Phosphoserine(IKK)HMM predict
2350O-linkedHMM predict
2373Phosphoserine(CAMK2)HMM predict
2375Phosphoserine(CK2)HMM predict
2375Phosphoserine(ATM)HMM predict
2381O-linkedHMM predict
2383Phosphoserine(CDC2)HMM predict
2383Phosphoserine(CDK)HMM predict
2430Phosphoserine(ATM)HMM predict
2453O-linkedHMM predict
2453Phosphoserine(CK1)HMM predict
2456O-linkedHMM predict
2457N-linkedHMM predict
2469N-linkedHMM predict
2472Phosphothreonine(CDK)HMM predict
2492Phosphothreonine(CDC2)HMM predict
2492Phosphothreonine(MAPK)HMM predict
2492Phosphothreonine(CDK)HMM predict
2499N-linkedHMM predict
2513MethylarginineHMM predict
2533Phosphoserine(CK1)HMM predict
2559O-linkedHMM predict
2737O-linkedHMM predict
2738O-linkedHMM predict
2826N-linkedHMM predict
2827O-linkedHMM predict
2828O-linkedHMM predict
2829O-linkedHMM predict
2832Phosphoserine(ATM)HMM predict
2839Phosphoserine(CK1)HMM predict
2841Phosphoserine(CK1)HMM predict
2869O-linkedHMM predict
2869Phosphoserine(IKK)HMM predict
2956Phosphoserine(CK2)HMM predict
2956Phosphoserine(CK2)HMM predict
2969Phosphoserine(CK2)HMM predict
2983Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_017780
  • Location:chr8 61753892-61942016
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 61735620 61735956 336 18105
CTCF CD4SISSRdata 61735620 61735956 336 18105
CTCF JurkatGSE12889 61735683 61735957 274 18073
CTCF G2GSE9613 61735679 61736143 464 17982
CTCF G2GSE9613 61753252 61754186 934 174
Myc K562GSE19551 61735640 61736013 373 18066
Nanog hESGSE18292 61751246 61751831 585 2354
Oct1 H2O2-HelaGSE14283 61742802 61742834 32 11075
Oct1 H2O2-HelaGSE14283 61752104 61752138 34 1772
Oct1 HelaGSE14283 61742803 61742832 29 11075
Oct1 HelaGSE14283 61749729 61749761 32 4148
Oct1 HelaGSE14283 61752104 61752144 40 1769
hScc1 BcellGSE12603 61735526 61736289 763 17985
hScc1 BcellGSE12603 61753394 61754186 792 103
hScc1 CdLSGSE12603 61735379 61736253 874 18077
hScc1 CdLSGSE12603 61753362 61754148 786 138
hScc1 G2GSE9613 61735642 61736184 542 17980
hScc1 G2GSE9613 61753296 61754186 890 152
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
RARG MCF7GSE15244 61952182 61952472 290 10311
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 61867412 61868914 1502 0
CTCF G2GSE9613 61754890 61755772 882 0
CTCF G2GSE9613 61837997 61838181 184 0
CTCF G2GSE9613 61849532 61849666 134 0
ER E2-MCF7GSE14664 61774078 61774113 35 0
FOXA1 DLD1GSE12801 61772803 61773377 574 0
FOXA1 DLD1GSE12801 61783561 61784426 865 0
FOXA1 MCF7GSE15244 61759411 61760342 931 0
FOXA1 MCF7GSE15244 61790088 61790409 321 0
FOXA1 MCF7GSE15244 61794249 61794418 169 0
GABP HelaGSE8489 61864602 61865260 658 0
GATA3 MCF7GSE15244 61783067 61783893 826 0
Myc K562GSE19551 61826768 61827031 263 0
Myc K562GSE19551 61882874 61883247 373 0
NRSF JurkatGSE13047 61849774 61850236 462 0
NRSF JurkatGSE13047 61910908 61911475 567 0
NRSF-mono JurkatQuESTdata 61911011 61911379 368 0
Oct1 H2O2-HelaGSE14283 61833645 61833673 28 0
Oct1 H2O2-HelaGSE14283 61853094 61853123 29 0
Oct1 H2O2-HelaGSE14283 61865125 61865169 44 0
Oct1 H2O2-HelaGSE14283 61909364 61909391 27 0
PAX3-FKHR Rh4GSE19063 61922315 61924164 1849 0
PHF8 Hs68minusFBSGSE20725 61826653 61827138 485 0
PolII HeLaGSE12783 61752818 61756027 3209 0
RARG MCF7GSE15244 61790115 61790409 294 0
Rb shRbQuiescentGSE19898 61813799 61814057 258 0
Stat6 IL-4-hr1GSE17850 61855793 61856697 904 0
TAF HelaGSE8489 61755690 61756838 1148 0
TAF HelaGSE8489 61789958 61790409 451 0
TFAP2C MCF7GSE21234 61789539 61789919 380 0
TFAP2C MCF7GSE21234 61817557 61818008 451 0
TFAP2C MCF7GSE21234 61837812 61838713 901 0
USF1 HepG2E 61864742 61868714 3972 0
hScc1 BcellGSE12603 61754890 61755772 882 0
hScc1 BcellGSE12603 61775623 61776044 421 0
hScc1 BcellGSE12603 61789380 61789958 578 0
hScc1 BcellGSE12603 61856060 61856462 402 0
hScc1 BcellGSE12603 61867932 61868297 365 0
hScc1 CdLSGSE12603 61755272 61755894 622 0
hScc1 CdLSGSE12603 61855988 61856633 645 0
hScc1 CdLSGSE12603 61867860 61868566 706 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
25495 mRNA CHD7 chr8 61753892 61942017 221 EST chr8 61930954 61931352Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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