AutismKB 2.0

Annotation Detail for SCYL2


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Basic Information Top
Gene Symbol:SCYL2 ( CVAK104,FLJ10074,KIAA1360 )
Gene Full Name: SCY1-like 2 (S. cerevisiae)
Band: 12q23.1
Quick LinksEntrez ID:55681; OMIM: NA; Uniprot ID:SCYL2_HUMAN; ENSEMBL ID: ENSG00000136021; HGNC ID: 19286
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
350Phosphoserine.
438Phosphothreonine.
440Phosphothreonine.
677Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
51N-linkedHMM predict
103Phosphothreonine(PKC)HMM predict
138Phosphoserine(CDC2)HMM predict
141Phosphoserine(CDC2)HMM predict
141Phosphoserine(MAPK)HMM predict
178N-linkedHMM predict
183N-linkedHMM predict
205N-linkedHMM predict
232Phosphotyrosine(SRC)HMM predict
275Phosphotyrosine(EGFR)HMM predict
275Phosphotyrosine(Syk)HMM predict
277Phosphoserine(CDK)HMM predict
290Phosphoserine(IKK)HMM predict
309N-linkedHMM predict
405Phosphotyrosine(EGFR)HMM predict
405Phosphotyrosine(INSR)HMM predict
448Phosphoserine(PKG)HMM predict
677Phosphoserine(PKA)HMM predict
679Phosphothreonine(PKC)HMM predict
732Phosphoserine(CK1)HMM predict
736O-linkedHMM predict
740Phosphoserine(IKK)HMM predict
741O-linkedHMM predict
743O-linkedHMM predict
743O-linkedHMM predict
744O-linkedHMM predict
745O-linkedHMM predict
748Phosphoserine(IKK)HMM predict
748O-linkedHMM predict
768N-linkedHMM predict
771N-linkedHMM predict
774N-linkedHMM predict
797Phosphoserine(CDC2)HMM predict
807Phosphothreonine(PKA)HMM predict
830Phosphothreonine(PKC)HMM predict
857Phosphoserine(ATM)HMM predict
874Phosphoserine(PKA)HMM predict
874O-linkedHMM predict
912O-linkedHMM predict
913O-linkedHMM predict
915O-linkedHMM predict
916N-linkedHMM predict
922N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_017988
  • Location:chr12 99185679-99258042
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
PHF8 Hs68plusFBSGSE20725 99184905 99186282 1377 86
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 99223324 99223366 42 0
ER Fulvestrant-MCF7GSE14664 99223323 99223366 43 0
H3K4me3 colorectalcancer 99185478 99186969 1491 0
H3ac HepG2E 99185701 99187362 1661 0
NFkBII GM12878GSE19485 99247038 99248564 1526 0
Oct1 HelaGSE14283 99214841 99214877 36 0
Oct1 HelaGSE14283 99223325 99223362 37 0
TAF HelaGSE8489 99185821 99186108 287 0
TFAP2C MCF7GSE21234 99197831 99198139 308 0
VDR GM10855-stimGSE22484 99240807 99244642 3835 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018