AutismKB 2.0

Annotation Detail for PACS1


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Basic Information Top
Gene Symbol:PACS1 ( FLJ10209,KIAA1175 )
Gene Full Name: phosphofurin acidic cluster sorting protein 1
Band: 11q13.1-q13.2
Quick LinksEntrez ID:55690; OMIM: 607492; Uniprot ID:PACS1_HUMAN; ENSEMBL ID: ENSG00000175115; HGNC ID: 30032
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
28Phosphoserine (By similarity).
46Phosphothreonine.
251Phosphotyrosine.
379Phosphoserine.
381Phosphoserine.
407Phosphoserine.
410Phosphoserine.
429Phosphothreonine (By similarity).
430Phosphoserine.
495Phosphoserine.
504Phosphothreonine.
528Phosphoserine.
529Phosphoserine.
534Phosphoserine.
Location(AA) Modifications Resource
28Phosphoserine (By similarity).Swiss-Prot 53.0
46Phosphothreonine.Swiss-Prot 53.0
46PhosphothreoninePhospho.ELM 6.0
278Phosphoserine (CK2
429Phosphothreonine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
21MethylarginineHMM predict
46Phosphothreonine(MAPK)HMM predict
46Phosphothreonine(CDK)HMM predict
54O-linkedHMM predict
55Phosphoserine(IKK)HMM predict
55O-linkedHMM predict
57O-linkedHMM predict
59Phosphoserine(CK1)HMM predict
60O-linkedHMM predict
66O-linkedHMM predict
69Phosphoserine(CK1)HMM predict
70Phosphoserine(CK1)HMM predict
71O-linkedHMM predict
72O-linkedHMM predict
73O-linkedHMM predict
74O-linkedHMM predict
84O-linkedHMM predict
95Phosphothreonine(MAPK)HMM predict
112Phosphoserine(IKK)HMM predict
202N-linkedHMM predict
255Phosphoserine(ATM)HMM predict
276N-linkedHMM predict
277Phosphotyrosine(INSR)HMM predict
277SulfotyrosineHMM predict
278Phosphoserine(CK2)HMM predict
278Phosphoserine(CK2)HMM predict
286Phosphoserine(CK1)HMM predict
287PhosphoserineHMM predict
292Phosphoserine(CK2)HMM predict
303Phosphotyrosine(Syk)HMM predict
303SulfotyrosineHMM predict
314Phosphothreonine(PKC)HMM predict
319Phosphothreonine(PKA)HMM predict
377N-linkedHMM predict
381Phosphoserine(ATM)HMM predict
390Phosphoserine(CK1)HMM predict
390Phosphoserine(IKK)HMM predict
407Phosphoserine(IKK)HMM predict
407Phosphoserine(ATM)HMM predict
411Phosphoserine(CK1)HMM predict
411Phosphoserine(IKK)HMM predict
411Phosphoserine(ATM)HMM predict
451Phosphoserine(IKK)HMM predict
495Phosphoserine(CDC2)HMM predict
495Phosphoserine(CDK)HMM predict
511Phosphothreonine(CDK)HMM predict
511Phosphothreonine(MAPK)HMM predict
519Phosphoserine(IKK)HMM predict
527N-linkedHMM predict
528Phosphoserine(CK2)HMM predict
528Phosphoserine(PKB)HMM predict
570N-linkedHMM predict
617N-linkedHMM predict
634Phosphotyrosine(EGFR)HMM predict
648N-linkedHMM predict
672Phosphotyrosine(Jak)HMM predict
731Phosphothreonine(PKC)HMM predict
742Phosphotyrosine(EGFR)HMM predict
779O-linkedHMM predict
779O-linkedHMM predict
780O-linkedHMM predict
780O-linkedHMM predict
781Phosphoserine(MAPK)HMM predict
781O-linkedHMM predict
795Phosphothreonine(MAPK)HMM predict
795O-linkedHMM predict
795PhosphothreonineHMM predict
795Phosphothreonine(CDK)HMM predict
798Phosphoserine(IKK)HMM predict
798O-linkedHMM predict
799Phosphoserine(CDK)HMM predict
811Phosphoserine(CDC2)HMM predict
848Phosphothreonine(PKC)HMM predict
864Phosphoserine(IKK)HMM predict
864O-linkedHMM predict
902Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_018026
  • Location:chr11 65594399-65768788
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 65593531 65593844 313 712
hScc1 CdLSGSE12603 65592399 65595551 3152 425
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 65764531 65768333 3802 0
CTCF CD4GSE12889 65658636 65658923 287 0
CTCF CD4GSE12889 65746677 65747089 412 0
CTCF CD4SISSRdata 65658636 65658923 287 0
CTCF CD4SISSRdata 65746677 65747089 412 0
CTCF HelaGSE12889 65746708 65747030 322 0
CTCF JurkatGSE12889 65746732 65747170 438 0
ER Breast-CancerGSE22609 65661356 65661999 643 0
ER E2-MCF7GSE14664 65689151 65689185 34 0
ER Fulvestrant-MCF7GSE14664 65620990 65621025 35 0
ER MCF7GSE19013 65661123 65661959 836 0
ER MCF7GSE19013 65719933 65720284 351 0
FOXA1 MCF7GSE15244 65637908 65638120 212 0
FOXA1 MCF7GSE15244 65648055 65648733 678 0
FOXA1 MCF7GSE15244 65651130 65651594 464 0
FOXA1 MCF7GSE15244 65666854 65667325 471 0
FOXA1 MCF7GSE15244 65705725 65706471 746 0
FOXA1 MCF7GSE15244 65713244 65713829 585 0
FOXA1 MCF7GSE15244 65716310 65716852 542 0
Fos K562GSE19551 65665908 65666373 465 0
Fos K562GSE19551 65712603 65713126 523 0
FoxA1 MCF7MACSdata 65637862 65638167 305 0
FoxA1 MCF7MACSdata 65670070 65670449 379 0
FoxA1 MCF7MACSdata 65719888 65720264 376 0
GATA3 MCF7GSE15244 65596522 65597369 847 0
H3ac HepG2E 65595140 65595940 800 0
H3ac HepG2E 65596522 65597120 598 0
H3ac HepG2E 65643529 65643775 246 0
H3ac HepG2E 65666703 65667002 299 0
KLF4 hESGSE17917 65602331 65602521 190 0
Myc K562GSE19551 65746690 65747070 380 0
NFkBII GM12878GSE19485 65659660 65662649 2989 0
NFkBII GM12878GSE19485 65745991 65747533 1542 0
NFkBII GM12892GSE19485 65746094 65747309 1215 0
NFkBII GM15510GSE19485 65746140 65747517 1377 0
NFkBII GM18526GSE19485 65745956 65747275 1319 0
NRSF pAbJurkat 65767241 65768695 1454 0
Oct1 H2O2-HelaGSE14283 65676049 65676090 41 0
Oct1 H2O2-HelaGSE14283 65768253 65768295 42 0
Oct1 HelaGSE14283 65619687 65619718 31 0
Oct1 HelaGSE14283 65642954 65642987 33 0
Oct1 HelaGSE14283 65759869 65759900 31 0
Oct1 HelaGSE14283 65760895 65760927 32 0
Oct1 HelaGSE14283 65768244 65768295 51 0
Oct4 hESGSE17917 65746828 65747073 245 0
P300 T30-glioblastomaGSE21026 65746474 65747343 869 0
Pol2 GM12878GSE19551 65655884 65656489 605 0
RARA MCF7GSE15244 65641922 65642345 423 0
RARA MCF7GSE15244 65648055 65648733 678 0
RARA MCF7GSE15244 65650322 65650780 458 0
RARA MCF7GSE15244 65713576 65713829 253 0
RARG MCF7GSE15244 65648055 65648733 678 0
RARG MCF7GSE15244 65651057 65651522 465 0
RARG MCF7GSE15244 65659263 65659444 181 0
RARG MCF7GSE15244 65713576 65713829 253 0
RARG MCF7GSE15244 65716240 65716816 576 0
TFAP2C MCF7GSE21234 65630669 65631426 757 0
TFAP2C MCF7GSE21234 65716075 65716821 746 0
USF1 HepG2E 65742921 65743782 861 0
USF1 HepG2E 65746179 65747063 884 0
USF1 HepG2E 65748503 65749361 858 0
USF2 HepG2E 65746179 65747063 884 0
hScc1 BcellGSE12603 65605509 65605736 227 0
hScc1 BcellGSE12603 65658254 65658946 692 0
hScc1 BcellGSE12603 65746478 65747063 585 0
hScc1 CdLSGSE12603 65658254 65658946 692 0
hScc1 CdLSGSE12603 65746395 65747063 668 0
hScc1 G2GSE9613 65746587 65747063 476 0
p130 QuiescentGSE19898 65643916 65644150 234 0
p130 SenescentGSE19898 65696298 65696453 155 0
p130 shRbSenescentGSE19898 65643792 65644098 306 0
p130 shRbSenescentGSE19898 65650865 65651221 356 0
p63 keratinocytesGSE17611 65666730 65667472 742 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
4734 mRNA PACS1 chr11 65594399 65768789 186 EST chr11 65603353 65603539 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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