AutismKB 2.0

Annotation Detail for POLR3B


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Basic Information Top
Gene Symbol:POLR3B ( C128,DKFZp686B10117,FLJ10388,RPC2 )
Gene Full Name: polymerase (RNA) III (DNA directed) polypeptide B
Band: 12q23.3
Quick LinksEntrez ID:55703; OMIM: NA; Uniprot ID:RPC2_HUMAN; ENSEMBL ID: ENSG00000013503; HGNC ID: 30348
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
202Phosphoserine.
206Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
10N-linkedHMM predict
22Phosphothreonine(PKC)HMM predict
67Phosphoserine(CK2)HMM predict
92N-linkedHMM predict
98Phosphoserine(IKK)HMM predict
185Phosphoserine(CK1)HMM predict
202Phosphoserine(IKK)HMM predict
205Phosphoserine(CK1)HMM predict
207Phosphothreonine(CDK)HMM predict
356PhosphotyrosineHMM predict
357Phosphotyrosine(Jak)HMM predict
357SulfotyrosineHMM predict
457Phosphoserine(ATM)HMM predict
466Phosphoserine(CAMK2)HMM predict
466Phosphoserine(PKG)HMM predict
466Phosphoserine(PKC)HMM predict
466PhosphoserineHMM predict
577N-linkedHMM predict
584Phosphotyrosine(Jak)HMM predict
678N-linkedHMM predict
683N-linkedHMM predict
738N-linkedHMM predict
778Phosphothreonine(PKC)HMM predict
784N-linkedHMM predict
816Phosphoserine(MAPK)HMM predict
829N-linkedHMM predict
851Phosphotyrosine(Syk)HMM predict
904O-linkedHMM predict
939Phosphothreonine(PKC)HMM predict
1036Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_018082
  • Location:chr12 105275618-105428104
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 105275444 105275728 284 33
CTCF CD4SISSRdata 105275444 105275728 284 33
CTCF JurkatGSE12889 105275368 105275809 441 30
hScc1 BcellGSE12603 105275257 105275676 419 152
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 105430273 105430490 217 2277
CTCF G2GSE9613 105439369 105439799 430 11480
ER E2-MCF7GSE14664 105433909 105434017 108 5859
Oct1 HelaGSE14283 105432729 105432810 81 4665
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 105304260 105304529 269 0
CTCF CD4SISSRdata 105304260 105304529 269 0
CTCF G2GSE9613 105275223 105276248 1025 0
CTCF G2GSE9613 105304285 105304491 206 0
CTCF G2GSE9613 105379787 105380112 325 0
CTCF G2GSE9613 105413875 105414075 200 0
ETS1 JurkatGSE17954 105275129 105276679 1550 0
FOXA1 MCF7GSE15244 105275637 105276360 723 0
Gata2 K562GSE18868 105275991 105276832 841 0
H3ac HepG2E 105276360 105276823 463 0
H3ac HepG2E 105277796 105278156 360 0
H3ac HepG2E 105278776 105279755 979 0
HIF1 HypoHepG2 105275637 105276208 571 0
HIF1 NormHepG2 105275504 105276208 704 0
Nanog ESGSE20650 105305818 105306105 287 0
Nanog hESGSE18292 105370253 105370708 455 0
Oct1 H2O2-HelaGSE14283 105357315 105357364 49 0
Oct1 H2O2-HelaGSE14283 105401046 105401076 30 0
Oct1 H2O2-HelaGSE14283 105415453 105415518 65 0
Oct1 HelaGSE14283 105319520 105319597 77 0
Oct1 HelaGSE14283 105401046 105401081 35 0
Oct1 HelaGSE14283 105407784 105407829 45 0
Oct4 hESGSE17917 105275525 105275887 362 0
P300 T30-glioblastomaGSE21026 105287235 105288142 907 0
P300 T30-glioblastomaGSE21026 105333025 105333445 420 0
PHF8 293TGSE20725 105275424 105276574 1150 0
PHF8 HeLaGSE20725 105275444 105276429 985 0
hScc1 BcellGSE12603 105304285 105304491 206 0
hScc1 CdLSGSE12603 105275223 105276283 1060 0
hScc1 CdLSGSE12603 105304285 105304491 206 0
hScc1 G2GSE9613 105275257 105276823 1566 0
p130 shRbQuiescentGSE19898 105275453 105276206 753 0
p130 shRbSenescentGSE19898 105275513 105276098 585 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
6547 mRNA POLR3B chr12 105253955 105406442 231 mRNA POLR3B chr12 105253219 105254186Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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