AutismKB 2.0

Annotation Detail for WDR11


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Basic Information Top
Gene Symbol:WDR11 ( BRWD2,DKFZp434L1715,DR11,FLJ42531,WDR15 )
Gene Full Name: WD repeat domain 11
Band: 10q26.12
Quick LinksEntrez ID:55717; OMIM: 606417; Uniprot ID:WDR11_HUMAN; ENSEMBL ID: ENSG00000120008; HGNC ID: 13831
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
402Phosphoserine.
406Phosphoserine.
1086Phosphotyrosine.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_018117
  • Location:chr10 122600684-122659024
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
GABP HelaGSE8489 122600073 122601267 1194 15
H3K4me2 HCT116GSE10453 122600073 122600460 387 418
Oct1 H2O2-HelaGSE14283 122599531 122599566 35 1136
Oct1 HelaGSE14283 122599494 122599567 73 1154
RARA MCF7GSE15244 122600073 122601014 941 141
RARG MCF7GSE15244 122600318 122601014 696 19
p130 SenescentGSE19898 122600424 122600902 478 22
p130 shRbSenescentGSE19898 122600510 122600853 343 3
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 122678230 122678804 574 19493
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 122600541 122600919 378 0
GABP k562GSE8489 122600073 122602610 2537 0
H3K4me3 colorectalcancer 122600073 122602122 2049 0
H3ac HepG2E 122601014 122602683 1669 0
NFkBII GM10847GSE19485 122600242 122601925 1683 0
NFkBII GM12878GSE19485 122600078 122602693 2615 0
NFkBII GM12892GSE19485 122600079 122601914 1835 0
NFkBII GM15510GSE19485 122600122 122601933 1811 0
NFkBII GM18526GSE19485 122600120 122601735 1615 0
Oct1 H2O2-HelaGSE14283 122608561 122608591 30 0
Oct1 HelaGSE14283 122637681 122637721 40 0
Oct1 HelaGSE14283 122649058 122649134 76 0
P300 T30-glioblastomaGSE21026 122600293 122601251 958 0
PHF8 293TGSE20725 122600344 122601313 969 0
PHF8 HeLaGSE20725 122600534 122601500 966 0
PHF8 Hs68plusFBSGSE20725 122600076 122601505 1429 0
PolII HeLaGSE12783 122600389 122601755 1366 0
RNAII Tamoxifen-MCF7GSE14664 122637685 122637720 35 0
RNAII Tamoxifen-MCF7GSE14664 122643219 122643311 92 0
Rb GrowingGSE19898 122600734 122600960 226 0
TAF k562GSE8489 122624726 122624975 249 0
TAFII hESGSE17917 122600580 122601173 593 0
hScc1 BcellGSE12603 122600568 122600941 373 0
hScc1 CdLSGSE12603 122600695 122601228 533 0
p130 QuiescentGSE19898 122600824 122601381 557 0
p130 QuiescentGSE19898 122641026 122641153 127 0
p130 SenescentGSE19898 122600984 122601199 215 0
p130 shRbQuiescentGSE19898 122600860 122601282 422 0
p130 shRbSenescentGSE19898 122600924 122601136 212 0
Validated miRNA targets Top
No data
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
1141 Unknown pSILAC miR-1 BRWD2 down 50-25% 18668040
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000120008 n_a n_a n_a "epithelium, lymphoblast, lymphocyte, leukocyte, muscle cell" "benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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