Annotation Detail for VPS35

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Basic Information Top

Gene Symbol:	VPS35 ( DKFZp434E1211,DKFZp434P1672,FLJ10752,FLJ13588,FLJ20388,MEM3 )
Gene Full Name:	vacuolar protein sorting 35 homolog (S. cerevisiae)
Band:	16q11.2
Quick Links	Entrez ID:55737; OMIM: 601501; Uniprot ID:VPS35_HUMAN; ENSEMBL ID: ENSG00000069329; HGNC ID: 13487
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:2 results
Experimental PTM Sites from dbPTM:0 results
Predicted PTM Sites by profile HMM from dbPTM:0 results

Location(AA)	Modification
7	Phosphoserine (By similarity).
791	Phosphotyrosine (By similarity).

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_018206
Location:chr16 45251091-45280592
strand:-

Upstream the gene:3 results
Downstream the gene:0 results
Inside the gene:17 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
PHF8	293T	GSE20725	45279769	45281809	2040	197
Rb	Senescent	GSE19898	45280418	45281184	766	209
p130	shRbQuiescent	GSE19898	45280256	45281242	986	157

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	45264790	45265143	353	0
CTCF	CD4	SISSRdata	45264790	45265143	353	0
CTCF	Hela	GSE12889	45264776	45265196	420	0
CTCF	G2	GSE9613	45264699	45265224	525	0
FOXA1	MCF7	GSE15244	45279678	45280284	606	0
H3K4me3	colorectal	cancer	45279099	45280040	941	0
H3ac	HepG2	E	45278155	45280258	2103	0
Myc	K562	GSE19551	45264884	45265205	321	0
Oct1	Hela	GSE14283	45260562	45260620	58	0
Rb	Growing	GSE19898	45279987	45280134	147	0
STAT1	IFN	SISSRdata	45264833	45265278	445	0
USF1	HepG2	E	45278360	45281851	3491	0
hScc1	Bcell	GSE12603	45264484	45265224	740	0
hScc1	Bcell	GSE12603	45279750	45280622	872	0
hScc1	CdLS	GSE12603	45264484	45265224	740	0
hScc1	G2	GSE9613	45264699	45265224	525	0
p130	shRbSenescent	GSE19898	45279709	45279946	237	0

Validated miRNA targets

Cis-Nats regulation

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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