AutismKB 2.0

Annotation Detail for ARFGAP1


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Basic Information Top
Gene Symbol:ARFGAP1 ( ARF1GAP,HRIHFB2281,MGC39924 )
Gene Full Name: ADP-ribosylation factor GTPase activating protein 1
Band: 20q13.33
Quick LinksEntrez ID:55738; OMIM: 608377; Uniprot ID:ARFG1_HUMAN; ENSEMBL ID: ENSG00000101199; HGNC ID: 15852
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
135Phosphothreonine.
189Phosphothreonine.
231N6-acetyllysine.
246Phosphoserine.
304Phosphoserine.
343Phosphoserine (By similarity).
345Phosphoserine (By similarity).
348Phosphoserine (By similarity).
361Phosphoserine (By similarity).
Location(AA) Modifications Resource
135Phosphothreonine.Swiss-Prot 53.0
135PhosphothreoninePhospho.ELM 6.0
189Phosphothreonine.Swiss-Prot 53.0
343Phosphoserine (By similarity).Swiss-Prot 53.0
345Phosphoserine (By similarity).Swiss-Prot 53.0
348Phosphoserine (By similarity).Swiss-Prot 53.0
361Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
125Phosphoserine(IKK)HMM predict
129Phosphoserine(CDC2)HMM predict
129Phosphoserine(IKK)HMM predict
129Phosphoserine(ATM)HMM predict
133N-linkedHMM predict
155Phosphoserine(IKK)HMM predict
159Phosphoserine(CDC2)HMM predict
189Phosphothreonine(MAPK)HMM predict
223Phosphoserine(PKB)HMM predict
234Phosphoserine(IKK)HMM predict
237Phosphoserine(ATM)HMM predict
237Phosphoserine(CAMK2)HMM predict
270Phosphoserine(CK1)HMM predict
273Phosphoserine(IKK)HMM predict
273Phosphoserine(ATM)HMM predict
295Phosphoserine(CDK)HMM predict
306Phosphoserine(CK1)HMM predict
306O-linkedHMM predict
340Phosphothreonine(PKC)HMM predict
343Phosphoserine(CDC2)HMM predict
343Phosphoserine(IKK)HMM predict
346Phosphoserine(ATM)HMM predict
348O-linkedHMM predict
361Phosphoserine(CK1)HMM predict
396ProlineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_018209
  • Location:chr20 61374609-61391585
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 61374162 61374975 813 41
H3ac HepG2E 61373778 61374062 284 690
PHF8 293TGSE20725 61374217 61374969 752 17
PHF8 HeLaGSE20725 61373804 61375283 1479 66
hScc1 BcellGSE12603 61366021 61366360 339 8419
hScc1 BcellGSE12603 61368030 61368903 873 6143
hScc1 BcellGSE12603 61374004 61375156 1152 30
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 61393144 61393344 200 1659
CTCF CD4SISSRdata 61393144 61393344 200 1659
CTCF JurkatGSE12889 61393114 61393336 222 1640
CTCF G2GSE9613 61393040 61393331 291 1600
hScc1 BcellGSE12603 61392372 61393331 959 1266
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 61380111 61380412 301 0
CTCF G2GSE9613 61382758 61383863 1105 0
H3K4me3 colorectalcancer 61375046 61375521 475 0
H3ac HepG2E 61375010 61377426 2416 0
P300 T30-glioblastomaGSE21026 61374344 61375070 726 0
Rb SenescentGSE19898 61375479 61376022 543 0
TFAP2C MCF7GSE21234 61375329 61376006 677 0
hScc1 BcellGSE12603 61379360 61379657 297 0
hScc1 BcellGSE12603 61385716 61385918 202 0
hScc1 BcellGSE12603 61386671 61387181 510 0
hScc1 BcellGSE12603 61387558 61387820 262 0
hScc1 BcellGSE12603 61388559 61388935 376 0
hScc1 BcellGSE12603 61390448 61390948 500 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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