AutismKB 2.0

Annotation Detail for PRKAR1B


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Basic Information Top
Gene Symbol:PRKAR1B ( PRKAR1 )
Gene Full Name: protein kinase, cAMP-dependent, regulatory, type I, beta
Band: 7p22.3
Quick LinksEntrez ID:5575; OMIM: 176911; Uniprot ID:KAP1_HUMAN; ENSEMBL ID: ENSG00000188191; HGNC ID: 9390
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine (Probable).
3Phosphoserine.
21Nitrated tyrosine.
77Phosphoserine.
83Phosphoserine.
100Pseudophosphorylation motif.
Location(AA) Modifications Resource
2N-acetylalanine (Probable).Swiss-Prot 53.0
21Nitrated tyrosine.Swiss-Prot 53.0
Location(AA) Modification Resource
71Phosphoserine(IKK)HMM predict
71Phosphoserine(PKB)HMM predict
73Phosphoserine(CK1)HMM predict
73Phosphoserine(ATM)HMM predict
73Phosphoserine(IKK)HMM predict
75Phosphoserine(ATM)HMM predict
77Phosphoserine(CK2)HMM predict
83O-linkedHMM predict
106Phosphothreonine(CK2)HMM predict
214Phosphothreonine(PKC)HMM predict
293Phosphotyrosine(Jak)HMM predict
293Phosphotyrosine(EGFR)HMM predict
312Phosphotyrosine(SRC)HMM predict
312Phosphotyrosine(Syk)HMM predict
323Phosphotyrosine(INSR)HMM predict
338Phosphothreonine(PKC)HMM predict
373Phosphotyrosine(EGFR)HMM predict
373TyrosineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002735
  • Location:chr7 555912-718658
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 718149 720074 1925 453
CTCF G2GSE9613 720429 720865 436 1989
hScc1 BcellGSE12603 718149 719211 1062 22
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER MCF7GSE19013 544364 544761 397 11350
TFAP2C MCF7GSE21234 544233 546760 2527 10416
p130 shRbQuiescentGSE19898 548967 549535 568 6662
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 598851 600692 1841 0
CBP JurkatGSE17954 642267 643753 1486 0
CBP T30-glioblastomaGSE21026 610093 611224 1131 0
CTCF CD4GSE12889 642702 642992 290 0
CTCF CD4SISSRdata 642702 642992 290 0
CTCF G2GSE9613 671344 671605 261 0
CTCF G2GSE9613 671916 672525 609 0
CTCF G2GSE9613 673784 674029 245 0
CTCF G2GSE9613 676563 677482 919 0
CTCF G2GSE9613 680340 680948 608 0
CTCF G2GSE9613 682598 683379 781 0
CTCF G2GSE9613 686365 686731 366 0
CTCF G2GSE9613 688016 688345 329 0
CTCF G2GSE9613 689198 690185 987 0
CTCF G2GSE9613 696965 697558 593 0
CTCF G2GSE9613 701599 701775 176 0
CTCF G2GSE9613 705067 705228 161 0
CTCF G2GSE9613 705706 706257 551 0
CTCF G2GSE9613 712901 713174 273 0
ETS1 JurkatGSE17954 610223 611244 1021 0
Fos K562GSE19551 591358 591995 637 0
KLF4 hESGSE17917 676804 677015 211 0
NFkBII GM12878GSE19485 599029 600383 1354 0
NFkBII GM12892GSE19485 598989 600325 1336 0
NFkBII GM15510GSE19485 599030 600310 1280 0
NFkBII GM15510GSE19485 607271 608728 1457 0
NRSF mAbJurkat 676665 677003 338 0
Nanog hESGSE18292 671714 671910 196 0
P300 T0-glioblastomaGSE21026 696629 696979 350 0
TFAP2C MCF7GSE21234 712850 713502 652 0
USF1 HepG2E 681146 681569 423 0
hScc1 BcellGSE12603 676598 677040 442 0
hScc1 BcellGSE12603 680340 680703 363 0
hScc1 BcellGSE12603 689831 690250 419 0
hScc1 BcellGSE12603 704930 705931 1001 0
hScc1 BcellGSE12603 717205 717664 459 0
p130 QuiescentGSE19898 663537 663751 214 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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