AutismKB 2.0

Annotation Detail for PRKAR2B


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Basic Information Top
Gene Symbol:PRKAR2B ( PRKAR2,RII-BETA )
Gene Full Name: protein kinase, cAMP-dependent, regulatory, type II, beta
Band: 7q22.3
Quick LinksEntrez ID:5577; OMIM: 176912; Uniprot ID:KAP3_HUMAN; ENSEMBL ID: ENSG00000005249; HGNC ID: 9392
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylserine (Probable).
83Phosphoserine.
85Phosphoserine.
114Phosphoserine.
Location(AA) Modifications Resource
2N-acetylserine (Probable).Swiss-Prot 53.0
113Phosphoserine (PKA
114Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
48Phosphothreonine(PKC)HMM predict
48Phosphothreonine(PKA)HMM predict
83Phosphoserine(CK2)HMM predict
83Phosphoserine(ATM)HMM predict
114Phosphoserine(PKB)HMM predict
114Phosphoserine(PKA)HMM predict
114Phosphoserine(PKG)HMM predict
114Phosphoserine(CAMK2)HMM predict
114Phosphoserine(CK2)HMM predict
202Phosphotyrosine(Jak)HMM predict
237O-linkedHMM predict
267Phosphotyrosine(EGFR)HMM predict
364Phosphoserine(PKB)HMM predict
370Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002736
  • Location:chr7 106472413-106589490
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 106472192 106472392 200 122
CTCF CD4SISSRdata 106472192 106472392 200 122
Fos K562GSE19551 106462912 106463567 655 9174
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 106575232 106575526 294 0
CTCF CD4GSE12889 106578184 106578498 314 0
CTCF CD4SISSRdata 106575232 106575526 294 0
CTCF CD4SISSRdata 106578184 106578498 314 0
CTCF G2GSE9613 106472214 106472691 477 0
CTCF G2GSE9613 106476087 106476694 607 0
CTCF G2GSE9613 106575125 106575592 467 0
ER MCF7GSE19013 106517937 106518562 625 0
ER MCF7GSE19013 106530901 106531373 472 0
GABP k562GSE8489 106541570 106541974 404 0
Myc K562GSE19551 106537456 106538082 626 0
Oct1 H2O2-HelaGSE14283 106547779 106547815 36 0
Oct1 H2O2-HelaGSE14283 106583194 106583220 26 0
Oct1 HelaGSE14283 106484247 106484284 37 0
Oct1 HelaGSE14283 106588816 106588849 33 0
P300 T30-glioblastomaGSE21026 106530874 106531642 768 0
Rb GrowingGSE19898 106538418 106538593 175 0
TFAP2C MCF7GSE21234 106531053 106531478 425 0
hScc1 BcellGSE12603 106472470 106472829 359 0
hScc1 BcellGSE12603 106578181 106578425 244 0
hScc1 CdLSGSE12603 106575125 106575557 432 0
hScc1 CdLSGSE12603 106577913 106578502 589 0
hScc1 G2GSE9613 106472172 106472895 723 0
hScc1 G2GSE9613 106575125 106575592 467 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
24479 mRNA PRKAR2B chr7 106279128 106396206 56508 EST chr7 106311621 106368129 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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