AutismKB 2.0

Annotation Detail for EXOC2


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Basic Information Top
Gene Symbol:EXOC2 ( FLJ11026,SEC5,SEC5L1,Sec5p )
Gene Full Name: exocyst complex component 2
Band: 6p25.3
Quick LinksEntrez ID:55770; OMIM: NA; Uniprot ID:EXOC2_HUMAN; ENSEMBL ID: ENSG00000112685; HGNC ID: 24968
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
432Phosphoserine.
435Phosphoserine (By similarity).
454N6-acetyllysine.
Location(AA) Modifications Resource
432Phosphoserine.Swiss-Prot 53.0
432PhosphoserinePhospho.ELM 6.0
435Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
44S-palmitoylHMM predict
86Phosphoserine(PKB)HMM predict
113SulfotyrosineHMM predict
113Phosphotyrosine(Syk)HMM predict
114Phosphotyrosine(Syk)HMM predict
145Phosphoserine(ATM)HMM predict
174N-linkedHMM predict
177N-linkedHMM predict
204Phosphotyrosine(Jak)HMM predict
325Phosphotyrosine(EGFR)HMM predict
411N-linkedHMM predict
422Phosphoserine(ATM)HMM predict
426Phosphoserine(PKC)HMM predict
432Phosphoserine(PKB)HMM predict
435Phosphoserine(CDK)HMM predict
445Phosphothreonine(CDC2)HMM predict
475N-linkedHMM predict
554Phosphothreonine(PKC)HMM predict
627S-palmitoylHMM predict
692Phosphoserine(MAPK)HMM predict
704Phosphoserine(CK1)HMM predict
845Phosphoserine(CDK)HMM predict
847Phosphoserine(CK1)HMM predict
870Phosphothreonine(CDK)HMM predict
870Phosphothreonine(MAPK)HMM predict
907MethionineHMM predict
920Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_018303
  • Location:chr6 430138-638108
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 637474 638765 1291 11
CTCF G2GSE9613 642406 642805 399 4497
CTCF G2GSE9613 646716 646959 243 8729
Myc K562GSE19551 648986 649409 423 11089
Oct4 hESGSE21916 637877 638540 663 100
p130 SenescentGSE19898 656042 656381 339 18103
p130 shRbQuiescentGSE19898 655716 656783 1067 18141
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 410546 410872 326 19430
CTCF G2GSE9613 418690 418999 309 11294
CTCF G2GSE9613 419321 419564 243 10696
ER MCF7GSE19013 419050 419658 608 10785
NFkBII GM12892GSE19485 415496 416849 1353 13966
hScc1 BcellGSE12603 416310 416556 246 13706
hScc1 CdLSGSE12603 419564 419895 331 10409
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 538237 538535 298 0
CTCF CD4SISSRdata 538237 538535 298 0
CTCF HelaGSE12889 496482 496672 190 0
CTCF G2GSE9613 448983 449277 294 0
CTCF G2GSE9613 459597 459882 285 0
CTCF G2GSE9613 460403 460708 305 0
CTCF G2GSE9613 461264 461522 258 0
CTCF G2GSE9613 467122 467866 744 0
CTCF G2GSE9613 478537 478793 256 0
CTCF G2GSE9613 496373 496697 324 0
CTCF G2GSE9613 502751 503132 381 0
CTCF G2GSE9613 506896 507221 325 0
CTCF G2GSE9613 511300 511523 223 0
CTCF G2GSE9613 546237 547620 1383 0
CTCF G2GSE9613 556299 556436 137 0
CTCF G2GSE9613 562448 562801 353 0
CTCF G2GSE9613 570001 570330 329 0
CTCF G2GSE9613 614530 614897 367 0
ETS1 JurkatGSE17954 637437 638602 1165 0
FoxA1 MCF7MACSdata 562534 562716 182 0
GABP k562GSE8489 464024 466291 2267 0
Gata2 K562GSE18868 549100 549998 898 0
H3K4me3 colorectalcancer 636732 637396 664 0
H3ac HepG2E 634642 635039 397 0
H3ac HepG2E 636732 637206 474 0
Myc K562GSE19551 524421 524723 302 0
NFkBII GM12892GSE19485 451060 452248 1188 0
Nanog ESGSE20650 527265 527755 490 0
PHF8 293TGSE20725 637224 638673 1449 0
PHF8 HeLaGSE20725 637372 638675 1303 0
PHF8 Hs68plusFBSGSE20725 637286 638721 1435 0
RARA MCF7GSE15244 620530 622149 1619 0
SRF HepG2GSE8489 479703 479913 210 0
Sox2 hESGSE18292 595330 595619 289 0
TAF HelaGSE8489 463998 466187 2189 0
TAF k562GSE8489 464058 466146 2088 0
TFAP2C MCF7GSE21234 496282 496791 509 0
TFAP2C MCF7GSE21234 562294 563004 710 0
TFAP2C MCF7GSE21234 604679 605292 613 0
c MYCMCF7 463960 466478 2518 0
hScc1 BcellGSE12603 464024 466367 2343 0
hScc1 BcellGSE12603 496337 496697 360 0
hScc1 BcellGSE12603 506896 507065 169 0
hScc1 BcellGSE12603 512049 512391 342 0
hScc1 BcellGSE12603 546359 547396 1037 0
hScc1 BcellGSE12603 637357 638059 702 0
hScc1 CdLSGSE12603 538067 538757 690 0
hScc1 CdLSGSE12603 631315 631821 506 0
p130 QuiescentGSE19898 502872 503084 212 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
22024 EST chr6 430397 432836 380 mRNA SEC5L1 chr6 430138 638109Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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