AutismKB 2.0

Annotation Detail for PRKCB


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Basic Information Top
Gene Symbol:PRKCB ( MGC41878,PKC-beta,PKCB,PRKCB1,PRKCB2 )
Gene Full Name: protein kinase C, beta
Band: 16p12.2-p12.1
Quick LinksEntrez ID:5579; OMIM: 176970; Uniprot ID:KPCB_HUMAN; ENSEMBL ID: ENSG00000166501; HGNC ID: 9395
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
16Phosphoserine; by autocatalysis
17Phosphothreonine; by autocatalysis
195Phosphotyrosine (By similarity).
314Phosphothreonine; by autocatalysis
324Phosphothreonine; by autocatalysis
500Phosphothreonine.
504Phosphothreonine.
635Phosphothreonine; by autocatalysis.
642Phosphothreonine.
661Phosphoserine; by autocatalysis.
Location(AA) Modifications Resource
2N-acetylalanine.Swiss-Prot 53.0
16Phosphoserine (by autocatalysis)(Potential).Swiss-Prot 53.0
17Phosphothreonine (by autocatalysis)(Potential).Swiss-Prot 53.0
314Phosphothreonine (by autocatalysis)(Potential).Swiss-Prot 53.0
324Phosphothreonine (by autocatalysis)(Potential).Swiss-Prot 53.0
500Phosphothreonine.Swiss-Prot 53.0
504Phosphothreonine.Swiss-Prot 53.0
635Phosphothreonine (by autocatalysis).Swiss-Prot 53.0
641PhosphothreoninePhospho.ELM 6.0
642Phosphothreonine.Swiss-Prot 53.0
661Phosphoserine (by autocatalysis) (Bysimilarity).Swiss-Prot 53.0
Location(AA) Modification Resource
11O-linkedHMM predict
17Phosphothreonine(PKC)HMM predict
70S-palmitoylHMM predict
71S-palmitoylHMM predict
195Phosphotyrosine(Jak)HMM predict
206Phosphoserine(IKK)HMM predict
214Phosphothreonine(PKC)HMM predict
224N-linkedHMM predict
241Phosphoserine(CK1)HMM predict
279Phosphoserine(ATM)HMM predict
285Phosphotyrosine(SRC)HMM predict
311Phosphoserine(ATM)HMM predict
311Phosphoserine(PKG)HMM predict
417Phosphotyrosine(Jak)HMM predict
507Phosphotyrosine(INSR)HMM predict
565Phosphoserine(CK1)HMM predict
602SulfotyrosineHMM predict
627Phosphothreonine(PKA)HMM predict
628Phosphoserine(PKA)HMM predict
642PhosphothreonineHMM predict
642Phosphothreonine(MAPK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002738
  • Location:chr16 23754822-24134807
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Myc K562GSE19551 23745479 23745873 394 9147
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 23796053 23796248 195 0
CTCF CD4GSE12889 23929330 23929624 294 0
CTCF CD4GSE12889 23955458 23955771 313 0
CTCF CD4GSE12889 23960894 23961208 314 0
CTCF CD4GSE12889 23989814 23990019 205 0
CTCF CD4SISSRdata 23796053 23796248 195 0
CTCF CD4SISSRdata 23929330 23929624 294 0
CTCF CD4SISSRdata 23955458 23955771 313 0
CTCF CD4SISSRdata 23960894 23961208 314 0
CTCF CD4SISSRdata 23989814 23990019 205 0
CTCF HelaGSE12889 23929379 23929612 233 0
CTCF HelaGSE12889 23989742 23989929 187 0
CTCF JurkatGSE12889 23955520 23955787 267 0
CTCF JurkatGSE12889 23960816 23961133 317 0
CTCF G2GSE9613 23754983 23755236 253 0
CTCF G2GSE9613 23929263 23929666 403 0
CTCF G2GSE9613 23955481 23955693 212 0
CTCF G2GSE9613 23960979 23961218 239 0
CTCF G2GSE9613 23964659 23965635 976 0
CTCF G2GSE9613 23989669 23990345 676 0
ER E2-MCF7GSE14664 23891385 23891464 79 0
ER E2-MCF7GSE14664 23904313 23904368 55 0
ER E2-MCF7GSE14664 23972518 23972573 55 0
ER E2-MCF7GSE14664 23972644 23972682 38 0
ER E2-MCF7GSE14664 24064993 24065178 185 0
ER Fulvestrant-MCF7GSE14664 24020181 24020213 32 0
ER Fulvestrant-MCF7GSE14664 24065078 24065129 51 0
Fos K562GSE19551 24069079 24069608 529 0
Gata2 K562GSE18868 23819510 23820930 1420 0
Gata2 K562GSE18868 23826108 23826726 618 0
KLF4 hESGSE17917 23754752 23754919 167 0
KLF4 hESGSE17917 24085674 24085839 165 0
Myc K562GSE19551 23870742 23871744 1002 0
Myc K562GSE19551 23921405 23921805 400 0
Myc K562GSE19551 23993289 23993827 538 0
NRSF JurkatGSE13047 23892820 23893448 628 0
NRSF JurkatGSE13047 24097132 24098301 1169 0
NRSF JurkatSISSRdata 24097313 24097798 485 0
NRSF mAbJurkat 23889949 23890616 667 0
NRSF mAbJurkat 23891436 23891712 276 0
NRSF mAbJurkat 23892781 23894520 1739 0
NRSF mAbJurkat 23895818 23896442 624 0
NRSF mAbJurkat 24093134 24094483 1349 0
NRSF mAbJurkat 24094815 24095370 555 0
NRSF mAbJurkat 24095741 24096195 454 0
NRSF mAbJurkat 24096770 24097625 855 0
NRSF mAbJurkat 24098225 24098728 503 0
NRSF mAbJurkat 24099081 24100113 1032 0
NRSF-mono JurkatQuESTdata 23892858 23893497 639 0
NRSF-mono JurkatQuESTdata 23920671 23920831 160 0
NRSF-mono JurkatQuESTdata 24097279 24097851 572 0
NRSF pAbJurkat 24097301 24097625 324 0
NRSF-poly JurkatQuESTdata 23892820 23893566 746 0
NRSF-poly JurkatQuESTdata 24097132 24098029 897 0
Nanog hESGSE18292 23784662 23785167 505 0
Nanog hESGSE18292 24017555 24018114 559 0
Oct1 H2O2-HelaGSE14283 23928831 23928863 32 0
Oct1 H2O2-HelaGSE14283 24013700 24013727 27 0
Oct1 H2O2-HelaGSE14283 24052032 24052061 29 0
Oct1 H2O2-HelaGSE14283 24072395 24072439 44 0
Oct1 H2O2-HelaGSE14283 24082370 24082399 29 0
Oct1 HelaGSE14283 23809668 23809740 72 0
Oct1 HelaGSE14283 23864658 23864687 29 0
Oct1 HelaGSE14283 23891392 23891461 69 0
Oct1 HelaGSE14283 23928831 23928863 32 0
Oct1 HelaGSE14283 24020181 24020224 43 0
Oct1 HelaGSE14283 24020709 24020739 30 0
Oct1 HelaGSE14283 24072395 24072439 44 0
Oct4 hESGSE21916 24017488 24018203 715 0
Oct4 hESGSE21916 24058171 24058527 356 0
Rb GrowingGSE19898 23965416 23965565 149 0
STAT1 HeLaGSE12782 23970695 23972525 1830 0
STAT1 HeLaGSE12782 24057924 24060129 2205 0
STAT1 HeLaGSE12783 23970706 23972491 1785 0
STAT1 HeLaGSE12783 24057958 24060095 2137 0
Sox2 hESGSE18292 23759238 23759645 407 0
Sox2 hESGSE18292 23955576 23955822 246 0
TAF HelaGSE8489 24033927 24034499 572 0
TFAP2C MCF7GSE21234 23823886 23824215 329 0
TFAP2C MCF7GSE21234 23909508 23909885 377 0
TFAP2C MCF7GSE21234 23995203 23995681 478 0
hScc1 BcellGSE12603 23755018 23755989 971 0
hScc1 BcellGSE12603 23926436 23926626 190 0
hScc1 BcellGSE12603 23929263 23929666 403 0
hScc1 BcellGSE12603 23943465 23943708 243 0
hScc1 BcellGSE12603 23955317 23955693 376 0
hScc1 BcellGSE12603 23960979 23961218 239 0
hScc1 BcellGSE12603 23989706 23990309 603 0
hScc1 CdLSGSE12603 23754712 23756016 1304 0
hScc1 CdLSGSE12603 23929263 23929666 403 0
hScc1 CdLSGSE12603 23955205 23955693 488 0
hScc1 CdLSGSE12603 23960979 23961218 239 0
hScc1 CdLSGSE12603 23989669 23990345 676 0
hScc1 G2GSE9613 23955445 23955693 248 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
9752 mRNA PRKCB1 chr16 23754822 24134824 419 mRNA chr16 23855426 23855845 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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