AutismKB 2.0

Annotation Detail for METTL2B


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Basic Information Top
Gene Symbol:METTL2B ( FLJ11350,FLJ12760,METL,METTL2,METTL2A,PSENIP1 )
Gene Full Name: methyltransferase like 2B
Band: 7q32.1
Quick LinksEntrez ID:55798; OMIM: 607846; Uniprot ID:MTL2B_HUMAN; ENSEMBL ID: ENSG00000165055; HGNC ID: 18272
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
154Phosphothreonine.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_018396
  • Location:chr7 127904018-127930212
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 127896956 127897170 214 6956
CTCF G2GSE9613 127901606 127901860 254 2286
NFkBII GM15510GSE19485 127903382 127904619 1237 18
NFkBII GM18526GSE19485 127903505 127904499 994 17
Nanog ESGSE20650 127896964 127897193 229 6940
Rb QuiescentGSE19898 127903810 127904071 261 78
Rb SenescentGSE19898 127903836 127904093 257 54
Rb shRbSenescenceGSE19898 127903837 127904023 186 89
TAF HelaGSE8489 127896218 127896571 353 7624
hScc1 BcellGSE12603 127901606 127901860 254 2286
hScc1 CdLSGSE12603 127901606 127901860 254 2286
hScc1 G2GSE9613 127901606 127901860 254 2286
p130 QuiescentGSE19898 127903788 127904050 262 100
p130 SenescentGSE19898 127903740 127904205 465 46
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 127944095 127944296 201 13983
hScc1 BcellGSE12603 127938180 127938461 281 8108
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 127903736 127904560 824 0
ETS1 JurkatGSE17954 127903474 127904924 1450 0
GABP k562GSE8489 127903283 127905517 2234 0
H3K4me2 HCT116GSE10453 127904591 127905517 926 0
H3K4me3 colorectalcancer 127904182 127905517 1335 0
H3ac HepG2E 127903445 127905517 2072 0
LIN9 G0GSE7516 127903736 127904387 651 0
P300 T30-glioblastomaGSE21026 127903459 127904722 1263 0
PHF8 Hs68plusFBSGSE20725 127903555 127904626 1071 0
PolII HeLaGSE12783 127903380 127904838 1458 0
TAF HelaGSE8489 127903445 127905517 2072 0
TAFII hESGSE17917 127903855 127904244 389 0
TFAP2C MCF7GSE21234 127921060 127921481 421 0
hScc1 BcellGSE12603 127903888 127904668 780 0
hScc1 CdLSGSE12603 127903765 127904422 657 0
hScc1 G2GSE9613 127903888 127904560 672 0
p130 shRbQuiescentGSE19898 127903746 127904367 621 0
p130 shRbSenescentGSE19898 127903848 127904210 362 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018