AutismKB 2.0

Annotation Detail for DOK5


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Basic Information Top
Gene Symbol:DOK5 ( C20orf180,MGC16926 )
Gene Full Name: docking protein 5
Band: 20q13.2
Quick LinksEntrez ID:55816; OMIM: 608334; Uniprot ID:DOK5_HUMAN; ENSEMBL ID: ENSG00000101134; HGNC ID: 16173
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
273DKFBH motif.
Location(AA) Modifications Resource
Location(AA) Modification Resource
13Phosphotyrosine(EGFR)HMM predict
142Phosphotyrosine(Syk)HMM predict
220Phosphotyrosine(SRC)HMM predict
220Phosphotyrosine(EGFR)HMM predict
244Phosphoserine(PKG)HMM predict
244Phosphoserine(IKK)HMM predict
256Phosphoserine(IKK)HMM predict
256Phosphoserine(CAMK2)HMM predict
256Phosphoserine(PKG)HMM predict
256O-linkedHMM predict
277Phosphoserine(CAMK2)HMM predict
289Phosphoserine(CDC2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_018431
  • Location:chr20 52525672-52701115
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 52525264 52525909 645 86
FOXA1 MCF7GSE15244 52506223 52506420 197 19351
FOXA1 eGFPGSE10845 52506223 52506420 197 19351
FoxA1 MCF7MACSdata 52506130 52506977 847 19119
Myc hESGSE17917 52525344 52525685 341 158
RARA MCF7GSE15244 52506223 52506420 197 19351
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 52718518 52718733 215 17510
CTCF CD4SISSRdata 52718518 52718733 215 17510
Nanog ESGSE20650 52711871 52712594 723 11117
Nanog hESGSE18292 52711949 52712464 515 11091
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 52699462 52699665 203 0
CTCF CD4SISSRdata 52699462 52699665 203 0
CTCF G2GSE9613 52529544 52530062 518 0
CTCF G2GSE9613 52699386 52699601 215 0
FOXA1 MCF7GSE15244 52698110 52698993 883 0
FOXA1 eGFPGSE10845 52698110 52698993 883 0
GATA3 MCF7GSE15244 52698184 52698993 809 0
H3K27me3 colorectalcancer 52526349 52527188 839 0
NRSF mAbJurkat 52548619 52548946 327 0
Nanog hESGSE18292 52529089 52529356 267 0
RARA MCF7GSE15244 52697526 52698993 1467 0
hScc1 BcellGSE12603 52591698 52591839 141 0
hScc1 BcellGSE12603 52696629 52697137 508 0
hScc1 BcellGSE12603 52699386 52699601 215 0
hScc1 CdLSGSE12603 52696711 52697137 426 0
hScc1 CdLSGSE12603 52699386 52699839 453 0
hScc1 G2GSE9613 52696749 52697137 388 0
hScc1 G2GSE9613 52699386 52699601 215 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018