AutismKB 2.0

Annotation Detail for PRKCG


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Basic Information Top
Gene Symbol:PRKCG ( MGC57564,PKC-gamma,PKCC,PKCG,SCA14 )
Gene Full Name: protein kinase C, gamma
Band: 19q13.42
Quick LinksEntrez ID:5582; OMIM: 176980; Uniprot ID:KPCG_HUMAN; ENSEMBL ID: ENSG00000126583; HGNC ID: 9402
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
195Phosphotyrosine.
197N6-acetyllysine.
312Phosphotyrosine (By similarity).
322Phosphoserine (By similarity).
330Phosphoserine (By similarity).
514Phosphothreonine.
518Phosphothreonine (By similarity).
648Phosphothreonine; by autocatalysis
655Phosphothreonine; by autocatalysis
687Phosphoserine (By similarity).
Location(AA) Modifications Resource
322Phosphoserine (By similarity).Swiss-Prot 53.0
330Phosphoserine (By similarity).Swiss-Prot 53.0
514Phosphothreonine (By similarity).Swiss-Prot 53.0
514PhosphothreoninePhospho.ELM 6.0
518Phosphothreonine (By similarity).Swiss-Prot 53.0
648Phosphothreonine (by autocatalysis)(Potential).Swiss-Prot 53.0
655Phosphothreonine (by autocatalysis)(Potential).Swiss-Prot 53.0
655PhosphothreoninePhospho.ELM 6.0
674PhosphothreoninePhospho.ELM 6.0
687Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
195Phosphotyrosine(Jak)HMM predict
206N-linkedHMM predict
224N-linkedHMM predict
230N-linkedHMM predict
241Phosphoserine(CK1)HMM predict
241Phosphoserine(PKG)HMM predict
285Phosphotyrosine(Jak)HMM predict
285Phosphotyrosine(SRC)HMM predict
285Phosphotyrosine(Syk)HMM predict
286Phosphotyrosine(Abl)HMM predict
320O-linkedHMM predict
322Phosphoserine(CDC2)HMM predict
322PhosphoserineHMM predict
322O-linkedHMM predict
326O-linkedHMM predict
326Phosphoserine(CDC2)HMM predict
328Phosphoserine(ATM)HMM predict
328Phosphoserine(CDK)HMM predict
328O-linkedHMM predict
330O-linkedHMM predict
330Phosphoserine(ATM)HMM predict
330Phosphoserine(CDC2)HMM predict
342Phosphoserine(CDC2)HMM predict
373Phosphoserine(CK1)HMM predict
373Phosphoserine(PKA)HMM predict
413MethylarginineHMM predict
426Phosphothreonine(CDC2)HMM predict
426Phosphothreonine(MAPK)HMM predict
514O-linkedHMM predict
514PhosphothreonineHMM predict
521Phosphotyrosine(INSR)HMM predict
634MethylarginineHMM predict
655Phosphothreonine(MAPK)HMM predict
675Phosphotyrosine(INSR)HMM predict
687Phosphoserine(IKK)HMM predict
687Phosphoserine(CDK)HMM predict
687Phosphoserine(CDC2)HMM predict
690O-linkedHMM predict
690Phosphoserine(IKK)HMM predict
690Phosphoserine(MAPK)HMM predict
690Phosphoserine(CDC2)HMM predict
693ProlineHMM predict
695ProlineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002739
  • Location:chr19 59077278-59102712
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 59076777 59077016 239 382
ETS1 JurkatGSE17954 59074133 59075079 946 2673
H3K27me3 colorectalcancer 59076777 59077016 239 382
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
SRF GMOGSE8489 59103703 59104042 339 1160
hScc1 BcellGSE12603 59104519 59104699 180 1897
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 59082245 59082841 596 0
CTCF CD4GSE12889 59077294 59077481 187 0
CTCF CD4GSE12889 59101870 59102151 281 0
CTCF CD4SISSRdata 59077294 59077481 187 0
CTCF CD4SISSRdata 59101870 59102151 281 0
CTCF G2GSE9613 59101603 59102224 621 0
ETS1 JurkatGSE17954 59088075 59088696 621 0
NRSF JurkatGSE13047 59091736 59092296 560 0
NRSF JurkatGSE13047 59095393 59095824 431 0
NRSF JurkatGSE13047 59097835 59098834 999 0
NRSF mAbJurkat 59086649 59087096 447 0
NRSF mAbJurkat 59091802 59092438 636 0
NRSF mAbJurkat 59092811 59093445 634 0
NRSF mAbJurkat 59094227 59094613 386 0
NRSF mAbJurkat 59094956 59096285 1329 0
NRSF mAbJurkat 59097997 59098344 347 0
NRSF mAbJurkat 59099300 59100455 1155 0
NRSF mAbJurkat 59101369 59101757 388 0
NRSF-mono JurkatQuESTdata 59091741 59092295 554 0
NRSF-mono JurkatQuESTdata 59097991 59098833 842 0
NRSF-poly JurkatQuESTdata 59091716 59092284 568 0
NRSF-poly JurkatQuESTdata 59097836 59098881 1045 0
NRSF-poly JurkatQuESTdata 59099292 59100459 1167 0
Oct1 HelaGSE14283 59100004 59100036 32 0
PHF8 293TGSE20725 59084331 59085149 818 0
RNAII Tamoxifen-MCF7GSE14664 59099999 59100035 36 0
SRF GMOGSE8489 59099774 59100455 681 0
STAT1 HeLaGSE12782 59083328 59085577 2249 0
STAT1 HeLaGSE12783 59083328 59085577 2249 0
STAT1 IFNSISSRdata 59084222 59085282 1060 0
TFAP2C MCF7GSE21234 59089756 59090220 464 0
hScc1 BcellGSE12603 59077160 59077783 623 0
hScc1 BcellGSE12603 59084370 59084895 525 0
hScc1 BcellGSE12603 59101715 59102614 899 0
hScc1 CdLSGSE12603 59101677 59102260 583 0
hScc1 G2GSE9613 59101603 59102326 723 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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