Annotation Detail for BIN3

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Basic Information Top

Gene Symbol:	BIN3 ( MGC14978 )
Gene Full Name:	bridging integrator 3
Band:	8p21.3
Quick Links	Entrez ID:55909; OMIM: 606396; Uniprot ID:BIN3_HUMAN; ENSEMBL ID: ENSG00000147439; HGNC ID: 1054
Relate to Another Database:	SFARIGene; denovo-db

Post Translation Modification

No data

Location(AA)	Modification	Resource
193	Phosphotyrosine(INSR)	HMM predict
248	Phosphoserine(PKG)	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	22586478	22586743	265	4005
CTCF	CD4	SISSRdata	22586478	22586743	265	4005
CTCF	G2	GSE9613	22585385	22585836	451	3005
CTCF	G2	GSE9613	22586413	22586873	460	4038
CTCF	G2	GSE9613	22588812	22589527	715	6564
CTCF	G2	GSE9613	22590904	22591333	429	8513
Fos	K562	GSE19551	22586459	22587223	764	4236
Myc	K562	GSE19551	22586352	22587136	784	4139
RARG	MCF7	GSE15244	22586413	22587130	717	4166
Rb	Quiescent	GSE19898	22582473	22582770	297	16
Rb	Senescent	GSE19898	22586374	22586973	599	4068
hScc1	Bcell	GSE12603	22586413	22586923	510	4063
hScc1	CdLS	GSE12603	22586413	22587020	607	4111
hScc1	G2	GSE9613	22586413	22587130	717	4166

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
CBP	T30-glioblastoma	GSE21026	22535749	22536439	690
CTCF	CD4	GSE12889	22536321	22536610	289
CTCF	CD4	SISSRdata	22536321	22536610	289
CTCF	Hela	GSE12889	22536411	22536618	207
CTCF	Jurkat	GSE12889	22536423	22536567	144
CTCF	G2	GSE9613	22534153	22535451	1298
CTCF	G2	GSE9613	22536037	22537716	1679
CTCF	G2	GSE9613	22539740	22540365	625
CTCF	G2	GSE9613	22541060	22541194	134
CTCF	G2	GSE9613	22542986	22543227	241
CTCF	G2	GSE9613	22543660	22543884	224
CTCF	G2	GSE9613	22572159	22572573	414
CTCF	G2	GSE9613	22578936	22579294	358
ETS1	Jurkat	GSE17954	22581950	22583089	1139
FOXA1	MCF7	GSE15244	22547284	22547856	572
GABP	Hela	GSE8489	22581168	22582246	1078
GABP	k562	GSE8489	22580051	22584240	4189
GATA3	MCF7	GSE15244	22572705	22573353	648
H3K4me2	HCT116	GSE10453	22580447	22581982	1535
H3K4me3	colorectal	cancer	22581280	22582173	893
H3ac	HepG2	E	22579954	22580812	858
H3ac	HepG2	E	22581280	22582317	1037
LIN9	S	GSE7516	22582018	22582609	591
NRSF	pAb	Jurkat	22540950	22541218	268
NRSF	pAb	Jurkat	22554182	22554876	694
NRSF	pAb	Jurkat	22579108	22579365	257
PHF8	HeLa	GSE20725	22581860	22583095	1235
RARA	MCF7	GSE15244	22572500	22573083	583
RARG	MCF7	GSE15244	22572642	22573083	441
Rb	Senescent	GSE19898	22582431	22582767	336
hScc1	Bcell	GSE12603	22536294	22536701	407
hScc1	Bcell	GSE12603	22540365	22540621	256
hScc1	Bcell	GSE12603	22540876	22541282	406
hScc1	CdLS	GSE12603	22536378	22536847	469
p130	shRbQuiescent	GSE19898	22571921	22572633	712
p130	shRbSenescent	GSE19898	22582496	22582704	208
p63	keratinocytes	GSE17611	22547314	22548264	950

Validated miRNA targets

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-miR-124	hsa-mir-124-1	8	20795863
hsa-miR-124	hsa-mir-124-2	8	20795863
hsa-miR-124	hsa-mir-124-3	20	20795863
hsa-miR-184	hsa-mir-184	15	20795863
hsa-miR-222	hsa-mir-222	X	20795863
hsa-miR-222*	hsa-mir-222	X	20795863
hsa-miR-31	hsa-mir-31	9	20795863
hsa-miR-31*	hsa-mir-31	9	20795863

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
25166	mRNA	KIAA1967	chr8	22518495	22533926	36	mRNA	BIN3	chr8	22533890	22582540	Sense/Antisense (SA) pairs

Simple Query:

Paper Collected: 6/30/2018

Last Update: 8/26/2018