AutismKB 2.0

Annotation Detail for PRKG2


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Basic Information Top
Gene Symbol:PRKG2 ( PRKGR2,cGKII )
Gene Full Name: protein kinase, cGMP-dependent, type II
Band: 4q21.21
Quick LinksEntrez ID:5593; OMIM: 601591; Uniprot ID:KGP2_HUMAN; ENSEMBL ID: ENSG00000138669; HGNC ID: 9416
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
354Nitrated tyrosine.
Location(AA) Modifications Resource
354Nitrated tyrosine.Swiss-Prot 53.0
Location(AA) Modification Resource
18Phosphoserine(IKK)HMM predict
20N-linkedHMM predict
97Phosphoserine(CDK)HMM predict
97Phosphoserine(CDC2)HMM predict
109Phosphothreonine(PKA)HMM predict
110Phosphoserine(PKG)HMM predict
126O-linkedHMM predict
239N-linkedHMM predict
245Phosphoserine(CAMK2)HMM predict
388N-linkedHMM predict
422Phosphoserine(PKA)HMM predict
448Phosphoserine(CDC2)HMM predict
499Phosphotyrosine(Abl)HMM predict
499Phosphotyrosine(SRC)HMM predict
500Phosphoserine(CK1)HMM predict
547Phosphoserine(IKK)HMM predict
589Phosphotyrosine(Jak)HMM predict
609PhosphothreonineHMM predict
613PhosphothreonineHMM predict
616Phosphotyrosine(INSR)HMM predict
616Phosphotyrosine(SRC)HMM predict
676Phosphothreonine(PKA)HMM predict
690N-linkedHMM predict
726Phosphoserine(CDC2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006259
  • Location:chr4 82228860-82345238
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 82354725 82355681 956 9965
CTCF G2GSE9613 82361163 82361451 288 16069
H3K27me3 colorectalcancer 82352417 82352687 270 7314
hScc1 BcellGSE12603 82354883 82355724 841 10065
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 H2O2-HelaGSE14283 82221272 82221299 27 7575
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 82343919 82344124 205 0
Nanog ESGSE20650 82293935 82294528 593 0
Oct1 H2O2-HelaGSE14283 82329509 82329538 29 0
Oct1 HelaGSE14283 82327272 82327298 26 0
p63 keratinocytesGSE17611 82256728 82257491 763 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
19896 EST chr4 82443272 82471424 28152 mRNA PRKG2 chr4 82367015 82483394 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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