AutismKB 2.0

Annotation Detail for SULF2


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Basic Information Top
Gene Symbol:SULF2 ( DKFZp313E091,FLJ44488,FLJ90554,HSULF-2,KIAA1247,MGC126411 )
Gene Full Name: sulfatase 2
Band: 20q13.12
Quick LinksEntrez ID:55959; OMIM: 610013; Uniprot ID:SULF2_HUMAN; ENSEMBL ID: ENSG00000196562; HGNC ID: 20392
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
14Phosphothreonine.
65N-linked (GlcNAc...) (Potential).
883-oxoalanine (Cys) (By similarity).
112N-linked (GlcNAc...) (Potential).
132N-linked (GlcNAc...) (Potential).
149N-linked (GlcNAc...) (Potential).
171N-linked (GlcNAc...) (Potential).
198N-linked (GlcNAc...).
241N-linked (GlcNAc...) (Potential).
561N-linked (GlcNAc...) (Potential).
608N-linked (GlcNAc...) (Potential).
717N-linked (GlcNAc...) (Potential).
754N-linked (GlcNAc...) (Potential).
764N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
65N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
883-oxoalanine (Cys) (By similarity).Swiss-Prot 53.0
112N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
132N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
149N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
171N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
198N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
241N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
561N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
608N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
717N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
754N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
764N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
65N-linkedHMM predict
88S-palmitoylHMM predict
89S-palmitoylHMM predict
94Phosphoserine(CK1)HMM predict
107Phosphotyrosine(INSR)HMM predict
107SulfotyrosineHMM predict
112N-linkedHMM predict
115Phosphoserine(CK1)HMM predict
132N-linkedHMM predict
136Phosphotyrosine(EGFR)HMM predict
149N-linkedHMM predict
152Phosphotyrosine(INSR)HMM predict
171N-linkedHMM predict
177N-linkedHMM predict
185Phosphoserine(PKA)HMM predict
191Phosphotyrosine(Syk)HMM predict
198N-linkedHMM predict
241N-linkedHMM predict
243Phosphoserine(ATM)HMM predict
286Phosphothreonine(PKC)HMM predict
298SulfotyrosineHMM predict
490Phosphoserine(PKG)HMM predict
561N-linkedHMM predict
591Phosphotyrosine(INSR)HMM predict
608N-linkedHMM predict
681Phosphoserine(PKB)HMM predict
717N-linkedHMM predict
750O-linkedHMM predict
754N-linkedHMM predict
755N-linkedHMM predict
757Phosphotyrosine(INSR)HMM predict
764N-linkedHMM predict
768N-linkedHMM predict
789Phosphotyrosine(SRC)HMM predict
842Phosphotyrosine(Syk)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_018837
  • Location:chr20 45719558-45848214
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 45848655 45848961 306 594
FOXA1 MCF7GSE15244 45850851 45851841 990 3132
FOXA1 MCF7GSE15244 45853573 45854620 1047 5882
FOXA1 eGFPGSE10845 45850851 45851841 990 3132
FOXA1 eGFPGSE10845 45853573 45854620 1047 5882
RARA MCF7GSE15244 45848391 45849553 1162 758
RARA MCF7GSE15244 45850734 45854620 3886 4463
RARA MCF7GSE15244 45857409 45858446 1037 9713
RARA MCF7GSE15244 45860550 45861222 672 12672
TFAP2C MCF7GSE21234 45850033 45854957 4924 4281
hScc1 BcellGSE12603 45848061 45848961 900 297
hScc1 BcellGSE12603 45857409 45857587 178 9284
hScc1 BcellGSE12603 45862049 45862231 182 13926
hScc1 BcellGSE12603 45862698 45863154 456 14712
hScc1 BcellGSE12603 45863958 45864122 164 15826
hScc1 CdLSGSE12603 45848655 45849209 554 718
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 45763382 45764468 1086 0
CBP T30-glioblastomaGSE21026 45797700 45798562 862 0
CTCF CD4GSE12889 45725883 45726224 341 0
CTCF CD4GSE12889 45740100 45740302 202 0
CTCF CD4GSE12889 45787473 45787792 319 0
CTCF CD4SISSRdata 45725883 45726224 341 0
CTCF CD4SISSRdata 45740100 45740302 202 0
CTCF CD4SISSRdata 45787473 45787792 319 0
CTCF HelaGSE12889 45739963 45740348 385 0
CTCF HelaGSE12889 45787508 45787817 309 0
CTCF JurkatGSE12889 45740073 45740269 196 0
CTCF JurkatGSE12889 45774723 45774916 193 0
CTCF G2GSE9613 45731340 45731730 390 0
CTCF G2GSE9613 45736355 45736980 625 0
CTCF G2GSE9613 45739951 45740675 724 0
CTCF G2GSE9613 45774599 45774862 263 0
CTCF G2GSE9613 45787733 45788297 564 0
CTCF G2GSE9613 45847263 45847490 227 0
FOXA1 MCF7GSE15244 45767031 45767691 660 0
FOXA1 MCF7GSE15244 45846009 45846997 988 0
FOXA1 eGFPGSE10845 45767031 45767691 660 0
FOXA1 eGFPGSE10845 45846009 45846997 988 0
Fos K562GSE19551 45796041 45796539 498 0
Fos K562GSE19551 45826520 45826969 449 0
Oct4 hESGSE21916 45750599 45751352 753 0
P300 T0-glioblastomaGSE21026 45763389 45764352 963 0
P300 T0-glioblastomaGSE21026 45797763 45798703 940 0
P300 T30-glioblastomaGSE21026 45748032 45749526 1494 0
P300 T30-glioblastomaGSE21026 45763265 45764572 1307 0
P300 T30-glioblastomaGSE21026 45797414 45798668 1254 0
RARA MCF7GSE15244 45844604 45846961 2357 0
TFAP2C MCF7GSE21234 45829988 45831330 1342 0
VDR GM10855-stimGSE22484 45820125 45821710 1585 0
VDR GM10855-stimGSE22484 45846387 45847755 1368 0
VDR GM10861-stimGSE22484 45820046 45821769 1723 0
VDR GM10861-stimGSE22484 45829911 45831039 1128 0
hScc1 BcellGSE12603 45725301 45725982 681 0
hScc1 BcellGSE12603 45727493 45727736 243 0
hScc1 BcellGSE12603 45735682 45736355 673 0
hScc1 BcellGSE12603 45739201 45739525 324 0
hScc1 BcellGSE12603 45739914 45740675 761 0
hScc1 BcellGSE12603 45741156 45741462 306 0
hScc1 BcellGSE12603 45774487 45774862 375 0
hScc1 BcellGSE12603 45779581 45779748 167 0
hScc1 BcellGSE12603 45787733 45788082 349 0
hScc1 BcellGSE12603 45844247 45844816 569 0
hScc1 BcellGSE12603 45847033 45847490 457 0
hScc1 CdLSGSE12603 45739850 45740560 710 0
hScc1 CdLSGSE12603 45774523 45774862 339 0
hScc1 CdLSGSE12603 45787733 45788009 276 0
hScc1 G2GSE9613 45739914 45740645 731 0
hScc1 G2GSE9613 45787733 45788297 564 0
hScc1 G2GSE9613 45847263 45847490 227 0
p130 shRbSenescentGSE19898 45748635 45749047 412 0
p63 keratinocytesGSE17611 45727230 45728367 1137 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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