AutismKB 2.0

Annotation Detail for SEPT3


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Basic Information Top
Gene Symbol:SEPT3 ( MGC133218,SEP3,bK250D10.3 )
Gene Full Name: septin 3
Band: 22q13.2
Quick LinksEntrez ID:55964; OMIM: 608314; Uniprot ID:SEPT3_HUMAN; ENSEMBL ID: ENSG00000100167; HGNC ID: 10750
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
91Phosphoserine (By similarity).
Location(AA) Modifications Resource
91Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
33Phosphoserine(IKK)HMM predict
41Phosphotyrosine(INSR)HMM predict
55Phosphothreonine(PKA)HMM predict
91Phosphoserine(PKG)HMM predict
145SulfotyrosineHMM predict
270Phosphotyrosine(INSR)HMM predict
270Phosphotyrosine(Syk)HMM predict
352O-linkedHMM predict
352Phosphothreonine(MAPK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_145733
  • Location:chr22 40702941-40724015
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 40692557 40692935 378 10196
CTCF CD4SISSRdata 40692557 40692935 378 10196
H3K27me3 colorectalcancer 40700842 40702135 1293 1453
Rb SenescentGSE19898 40692583 40692908 325 10196
hScc1 BcellGSE12603 40692488 40693015 527 10190
hScc1 BcellGSE12603 40696211 40696758 547 6457
hScc1 BcellGSE12603 40697213 40697695 482 5488
hScc1 BcellGSE12603 40701783 40703442 1659 329
hScc1 CdLSGSE12603 40692488 40692981 493 10207
hScc1 G2GSE9613 40692488 40692981 493 10207
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 40702981 40703317 336 0
hScc1 BcellGSE12603 40708877 40709295 418 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
17541 mRNA SEPT3 chr22 40697495 40718723 91 EST chr22 40701807 40702721Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018