AutismKB 2.0

Annotation Detail for KLHL7


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Basic Information Top
Gene Symbol:KLHL7 ( KLHL6,SBBI26 )
Gene Full Name: kelch-like 7 (Drosophila)
Band: 7p15.3
Quick LinksEntrez ID:55975; OMIM: 611119; Uniprot ID:KLHL7_HUMAN; ENSEMBL ID: ENSG00000122550; HGNC ID: 15646
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
14Phosphothreonine(PKC)HMM predict
191Phosphothreonine(PKA)HMM predict
208Phosphotyrosine(Syk)HMM predict
208Phosphotyrosine(SRC)HMM predict
208Phosphotyrosine(EGFR)HMM predict
301Phosphoserine(ATM)HMM predict
370Phosphothreonine(MAPK)HMM predict
385Phosphotyrosine(INSR)HMM predict
433Phosphotyrosine(INSR)HMM predict
442N-linkedHMM predict
500Phosphotyrosine(Syk)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_018846
  • Location:chr7 23111926-23181445
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 23092154 23092985 831 19357
CTCF CD4GSE12889 23092194 23092429 235 19615
CTCF CD4SISSRdata 23092194 23092429 235 19615
CTCF JurkatGSE12889 23092224 23092444 220 19593
CTCF G2GSE9613 23092236 23092555 319 19531
CTCF G2GSE9613 23096434 23096764 330 15328
H3K4me3 colorectalcancer 23111123 23111589 466 571
LIN9 G0GSE7516 23111410 23112258 848 93
Myc K562GSE19551 23092164 23092532 368 19579
NRSF mAbJurkat 23111227 23111742 515 442
Oct1 HelaGSE14283 23096805 23096833 28 15108
P300 T0-glioblastomaGSE21026 23091917 23092804 887 19566
P300 T30-glioblastomaGSE21026 23091944 23092868 924 19521
PHF8 HeLaGSE20725 23111277 23112551 1274 13
Rb QuiescentGSE19898 23111690 23111952 262 106
Rb SenescentGSE19898 23111635 23111914 279 152
Rb shRbQuiescentGSE19898 23111703 23112023 320 64
Rb shRbSenescenceGSE19898 23111709 23111892 183 126
STAT1 IFNSISSRdata 23092134 23092640 506 19540
TFAP2C MCF7GSE21234 23111530 23112024 494 150
hScc1 BcellGSE12603 23111626 23112039 413 94
hScc1 CdLSGSE12603 23092236 23092768 532 19425
p130 SenescentGSE19898 23111632 23112095 463 63
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 23111626 23112258 632 0
ER E2-MCF7GSE14664 23158294 23158335 41 0
H3K4me3 colorectalcancer 23112075 23113071 996 0
H3ac HepG2E 23112223 23113469 1246 0
Nanog ESGSE20650 23121882 23122694 812 0
Nanog hESGSE18292 23122016 23122635 619 0
Oct1 H2O2-HelaGSE14283 23151257 23151288 31 0
Oct1 HelaGSE14283 23122634 23122662 28 0
Oct1 HelaGSE14283 23151257 23151287 30 0
Oct1 HelaGSE14283 23157469 23157500 31 0
Oct1 HelaGSE14283 23171477 23171510 33 0
RNAII Tamoxifen-MCF7GSE14664 23172038 23172073 35 0
p130 shRbSenescentGSE19898 23111621 23112396 775 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018