Annotation Detail for MAPK8
Basic Information Top
| Gene Symbol: | MAPK8 ( JNK,JNK1,JNK1A2,JNK21B1/2,PRKM8,SAPK1 ) |
|---|---|
| Gene Full Name: | mitogen-activated protein kinase 8 |
| Band: | 10q11.22 |
| Quick Links | Entrez ID:5599; OMIM: 601158; Uniprot ID:MK08_HUMAN; ENSEMBL ID: ENSG00000107643; HGNC ID: 6881 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 155 | Phosphoserine. | |
| 183 | Phosphothreonine. | |
| 185 | Phosphotyrosine. | |
| 185 | TXY. | |
| 255 | Phosphothreonine. | |
| 258 | Phosphothreonine. | |
| 259 | Phosphotyrosine. | |
| 308 | N6-acetyllysine. | |
| 357 | Phosphotyrosine. | |
| 367 | Phosphothreonine. | |
| 377 | Phosphoserine. | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 183 | Phosphothreonine. | Swiss-Prot 53.0 |
| 183 | Phosphothreonine (MAP2K7) | Phospho.ELM 6.0 |
| 185 | Phosphotyrosine. | Swiss-Prot 53.0 |
| 185 | Phosphotyrosine (MAP2K4;MAP2K) | Phospho.ELM 6.0 |
| 377 | Phosphoserine (By similarity). | Swiss-Prot 53.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 63 | N-linked | HMM predict |
| 71 | Phosphotyrosine(EGFR) | HMM predict |
| 183 | Phosphothreonine | HMM predict |
| 311 | Phosphoserine(PKG) | HMM predict |
| 311 | Phosphoserine(CAMK2) | HMM predict |
| 377 | Phosphoserine(CDC2) | HMM predict |
| 385 | N-linked | HMM predict |
| 393 | Phosphoserine(CK1) | HMM predict |
| 395 | Phosphoserine(IKK) | HMM predict |
| 395 | Phosphoserine(CK1) | HMM predict |
| 400 | O-linked | HMM predict |
| 414 | Phosphoserine(CK1) | HMM predict |
| 426 | Cysteine | HMM predict |
- RefSeq ID: NM_002750
- Location:chr10 49279692-49313187
- strand:+
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| Myc | K562 | GSE19551 | 49267365 | 49267547 | 182 | 12237 |
| Nanog | hES | GSE18292 | 49261488 | 49261772 | 284 | 18063 |
| P300 | T30-glioblastoma | GSE21026 | 49277980 | 49278901 | 921 | 1252 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| P300 | T30-glioblastoma | GSE21026 | 49316990 | 49317735 | 745 | 4175 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| Oct1 | Hela | GSE14283 | 49282762 | 49282800 | 38 | 0 |
| RARG | MCF7 | GSE15244 | 49294884 | 49295415 | 531 | 0 |
| p63 | keratinocytes | GSE17611 | 49295381 | 49296048 | 667 | 0 |
| Micro RNA Name | Stem Loop Name | The chromosome that miRNA located | Publication |
|---|---|---|---|
| hsa-miR-101 | hsa-mir-101-1 | 1 | 21068409 |
| hsa-miR-101 | hsa-mir-101-2 | 9 | 21068409 |
| hsa-miR-126 | hsa-mir-126 | 9 | 20859756 |
| hsa-miR-126* | hsa-mir-126 | 9 | 20859756 |
| hsa-miR-142-3p | hsa-mir-142 | 17 | 20859756 |
| hsa-miR-146a | hsa-mir-146a | 5 | 20859756 |
| hsa-miR-146a | hsa-mir-146a | 5 | 20525168 |
| hsa-miR-146a* | hsa-mir-146a | 5 | 20859756 |
| hsa-miR-146a* | hsa-mir-146a | 5 | 20525168 |
| hsa-miR-146b-3p | hsa-mir-146b | 10 | 19786024 |
| hsa-miR-146b-5p | hsa-mir-146b | 10 | 19786024 |
| hsa-miR-152 | hsa-mir-152 | 17 | 20859756 |
| hsa-miR-155 | hsa-mir-155 | 21 | 20937844 |
| hsa-miR-155 | hsa-mir-155 | 21 | 20859756 |
| hsa-miR-155 | hsa-mir-155 | 21 | 18048365 |
| hsa-miR-155 | hsa-mir-155 | 21 | 17242365 |
| hsa-miR-155* | hsa-mir-155 | 21 | 20937844 |
| hsa-miR-155* | hsa-mir-155 | 21 | 20859756 |
| hsa-miR-155* | hsa-mir-155 | 21 | 18048365 |
| hsa-miR-155* | hsa-mir-155 | 21 | 17242365 |
| hsa-miR-199a-3p | hsa-mir-199a-1 | 19 | 18456660 |
| hsa-miR-199a-3p | hsa-mir-199a-2 | 1 | 18456660 |
| hsa-miR-199a-5p | hsa-mir-199a-1 | 19 | 18456660 |
| hsa-miR-205 | hsa-mir-205 | 1 | 20859756 |
| hsa-miR-214 | hsa-mir-214 | 1 | 19859982 |
| hsa-miR-214* | hsa-mir-214 | 1 | 19859982 |
| hsa-miR-221 | hsa-mir-221 | X | 20576614 |
| hsa-miR-221* | hsa-mir-221 | X | 20576614 |
| hsa-miR-26a | hsa-mir-26a-1 | 3 | 20080666 |
| hsa-miR-26a | hsa-mir-26a-2 | 12 | 20080666 |
| hsa-miR-365 | hsa-mir-365-1 | 16 | 20859756 |
| hsa-miR-365 | hsa-mir-365-2 | 17 | 20859756 |
| hsa-miR-449a | hsa-mir-449a | 5 | 20859756 |
| hsa-miR-449b | hsa-mir-449b | 5 | 20859756 |
| hsa-miR-518c | hsa-mir-518c | 19 | 20859756 |
| hsa-miR-518c* | hsa-mir-518c | 19 | 20859756 |
| hsa-miR-552 | hsa-mir-552 | 1 | 20859756 |
| hsa-miR-584 | hsa-mir-584 | 5 | 20859756 |
| hsa-miR-615-3p | hsa-mir-615 | 12 | 20859756 |
| hsa-miR-615-5p | hsa-mir-615 | 12 | 20859756 |
| hsa-miR-622 | hsa-mir-622 | 13 | 20859756 |
| hsa-miR-630 | hsa-mir-630 | 15 | 20859756 |
| No data |
Cis-Nats regulation