AutismKB 2.0

Annotation Detail for MAPK11


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MAPK11 ( P38B,P38BETA2,PRKM11,SAPK2,SAPK2B,p38-2,p38Beta )
Gene Full Name: mitogen-activated protein kinase 11
Band: 22q13.33
Quick LinksEntrez ID:5600; OMIM: 602898; Uniprot ID:MK11_HUMAN; ENSEMBL ID: ENSG00000185386; HGNC ID: 6873
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
180Phosphothreonine (Probable).
182TXY.
182Phosphotyrosine.
Location(AA) Modifications Resource
180Phosphothreonine (Probable).Swiss-Prot 53.0
182Phosphotyrosine (Probable).Swiss-Prot 53.0
Location(AA) Modification Resource
14N-linkedHMM predict
32O-linkedHMM predict
61Phosphoserine(CDK)HMM predict
68Phosphothreonine(PKC)HMM predict
201N-linkedHMM predict
243Phosphoserine(MAPK)HMM predict
243Phosphoserine(CDC2)HMM predict
298Phosphoserine(CK2)HMM predict
298Phosphoserine(PKG)HMM predict
309Phosphoserine(ATM)HMM predict
311Phosphotyrosine(INSR)HMM predict
311Phosphotyrosine(Syk)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002751
  • Location:chr22 49044269-49050905
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 49055006 49055193 187 4194
CTCF CD4SISSRdata 49055006 49055193 187 4194
CTCF G2GSE9613 49056572 49057341 769 6051
NRSF JurkatGSE13047 49050845 49052910 2065 972
NRSF-mono JurkatQuESTdata 49050937 49052532 1595 829
NRSF-poly JurkatQuESTdata 49050582 49052571 1989 671
Rb GrowingGSE19898 49051401 49051539 138 565
TFAP2C MCF7GSE21234 49062380 49062730 350 11650
TFAP2C MCF7GSE21234 49063015 49063848 833 12526
VDR GM10861-UnstimGSE22484 49056428 49057473 1045 6045
hScc1 BcellGSE12603 49052838 49053400 562 2214
hScc1 BcellGSE12603 49054789 49055180 391 4079
hScc1 CdLSGSE12603 49056693 49057160 467 6021
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
hScc1 BcellGSE12603 49043440 49044271 831 414
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 49048279 49048536 257 0
CTCF CD4SISSRdata 49048279 49048536 257 0
CTCF G2GSE9613 49044533 49044886 353 0
hScc1 BcellGSE12603 49044566 49044845 279 0
hScc1 BcellGSE12603 49047822 49049005 1183 0
hScc1 BcellGSE12603 49049255 49050159 904 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-122 hsa-mir-122 18 19296470
hsa-miR-122* hsa-mir-122 18 19296470
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved