AutismKB 2.0

Annotation Detail for MAPK9


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MAPK9 ( JNK-55,JNK2,JNK2A,JNK2ALPHA,JNK2B,JNK2BETA,PRKM9,SAPK,p54a,p54aSAPK )
Gene Full Name: mitogen-activated protein kinase 9
Band: 5q35.3
Quick LinksEntrez ID:5601; OMIM: 602896; Uniprot ID:MK09_HUMAN; ENSEMBL ID: ENSG00000050748; HGNC ID: 6886
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
183Phosphothreonine.
185TXY.
185Phosphotyrosine.
404Phosphothreonine.
Location(AA) Modifications Resource
183Phosphothreonine.Swiss-Prot 53.0
183Phosphothreonine (MAP2K7)Phospho.ELM 6.0
185Phosphotyrosine.Swiss-Prot 53.0
185Phosphotyrosine (MAP2K4)Phospho.ELM 6.0
404Phosphothreonine (CK2 alpha;MA)Phospho.ELM 6.0
407Phosphoserine (CK2 alpha;MA)Phospho.ELM 6.0
Location(AA) Modification Resource
63N-linkedHMM predict
71Phosphotyrosine(EGFR)HMM predict
105Phosphotyrosine(Syk)HMM predict
183PhosphothreonineHMM predict
243Phosphothreonine(MAPK)HMM predict
311Phosphoserine(CK2)HMM predict
338Phosphotyrosine(Syk)HMM predict
382O-linkedHMM predict
384N-linkedHMM predict
386Phosphothreonine(MAPK)HMM predict
386O-linkedHMM predict
388Phosphoserine(IKK)HMM predict
388Phosphoserine(ATM)HMM predict
400PhosphoserineHMM predict
400Phosphoserine(IKK)HMM predict
411Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002752
  • Location:chr5 179595389-179640215
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
LIN9 G0GSE7516 179648102 179648341 239 8006
TFAP2C MCF7GSE21234 179649025 179649612 587 9103
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 179610898 179611702 804 0
CTCF G2GSE9613 179612556 179613346 790 0
H3K4me3 colorectalcancer 179618669 179619208 539 0
H3K4me3 colorectalcancer 179619698 179619971 273 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-141 hsa-mir-141 12 20053927
hsa-miR-141* hsa-mir-141 12 20053927
hsa-miR-17 hsa-mir-17 13 18700987
hsa-miR-17* hsa-mir-17 13 18700987
hsa-miR-199a-3p hsa-mir-199a-1 19 18456660
hsa-miR-199a-3p hsa-mir-199a-2 1 18456660
hsa-miR-199a-5p hsa-mir-199a-1 19 18456660
hsa-miR-205 hsa-mir-205 1 20065103
hsa-miR-224 hsa-mir-224 X 20065103
hsa-miR-335 hsa-mir-335 7 20065103
hsa-miR-335* hsa-mir-335 7 20065103
hsa-miR-424 hsa-mir-424 X 20065103
hsa-miR-424* hsa-mir-424 X 20065103
hsa-miR-451 hsa-mir-451 17 20065103
hsa-miR-491-3p hsa-mir-491 9 20065103
hsa-miR-491-5p hsa-mir-491 9 20065103
hsa-miR-92a hsa-mir-92a-1 13 18700987
hsa-miR-92a hsa-mir-92a-2 X 18700987
hsa-miR-93 hsa-mir-93 7 20065103
hsa-miR-93* hsa-mir-93 7 20065103
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018