AutismKB 2.0

Annotation Detail for MAPK10


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Basic Information Top
Gene Symbol:MAPK10 ( FLJ12099,FLJ33785,JNK3,JNK3A,MGC50974,PRKM10,p493F12,p54bSAPK )
Gene Full Name: mitogen-activated protein kinase 10
Band: 4q21.3
Quick LinksEntrez ID:5602; OMIM: 602897; Uniprot ID:MK10_HUMAN; ENSEMBL ID: ENSG00000109339; HGNC ID: 6872
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
221Phosphothreonine.
223Phosphotyrosine.
223TXY.
415Phosphoserine.
417Phosphoserine.
Location(AA) Modifications Resource
221Phosphothreonine.Swiss-Prot 53.0
221Phosphothreonine (MAP2K
223Phosphotyrosine.Swiss-Prot 53.0
223Phosphotyrosine (MAP2K4)Phospho.ELM 6.0
Location(AA) Modification Resource
38N-linkedHMM predict
101N-linkedHMM predict
109Phosphotyrosine(EGFR)HMM predict
143Phosphotyrosine(Syk)HMM predict
221PhosphothreonineHMM predict
376Phosphotyrosine(Syk)HMM predict
415O-linkedHMM predict
415Phosphoserine(CDC2)HMM predict
417O-linkedHMM predict
422N-linkedHMM predict
424O-linkedHMM predict
424O-linkedHMM predict
426O-linkedHMM predict
426O-linkedHMM predict
440Phosphoserine(IKK)HMM predict
451Phosphoserine(CK1)HMM predict
463CysteineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002753
  • Location:chr4 87156656-87593306
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Nanog hESGSE18292 87606794 87607184 390 13683
Nanog hESGSE18292 87612936 87613135 199 19729
Oct1 H2O2-HelaGSE14283 87606452 87606480 28 13160
Oct1 H2O2-HelaGSE14283 87613026 87613063 37 19738
Oct1 HelaGSE14283 87606445 87606483 38 13158
Oct1 HelaGSE14283 87613026 87613063 37 19738
Sox2 hESGSE18292 87606787 87607254 467 13714
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 87561706 87562031 325 0
Oct1 H2O2-HelaGSE14283 87566768 87566795 27 0
Oct1 HelaGSE14283 87563799 87563829 30 0
Oct1 HelaGSE14283 87563867 87563894 27 0
Oct1 HelaGSE14283 87583383 87583418 35 0
TAF HelaGSE8489 87571030 87571197 167 0
TFAP2C MCF7GSE21234 87520269 87520802 533 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
19936 mRNA chr4 87398140 87498257 100117 mRNA MAPK10 chr4 87294810 87632922 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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