Annotation Detail for MAP2K5
Basic Information Top
| Gene Symbol: | MAP2K5 ( HsT17454,MAPKK5,MEK5,PRKMK5 ) |
|---|---|
| Gene Full Name: | mitogen-activated protein kinase kinase 5 |
| Band: | 15q23 |
| Quick Links | Entrez ID:5607; OMIM: 602520; Uniprot ID:MP2K5_HUMAN; ENSEMBL ID: ENSG00000137764; HGNC ID: 6845 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 133 | Phosphoserine. | |
| 137 | Phosphoserine. | |
| 148 | Phosphoserine. | |
| 149 | Phosphoserine. | |
| 311 | Phosphoserine. | |
| 315 | Phosphothreonine. | |
| 316 | Phosphotyrosine. | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 129 | Phosphoserine (MAPK7) | Phospho.ELM 6.0 |
| 137 | Phosphoserine (MAPK7) | Phospho.ELM 6.0 |
| 142 | Phosphoserine (MAPK7) | Phospho.ELM 6.0 |
| 149 | Phosphoserine (MAPK7) | Phospho.ELM 6.0 |
| 311 | Phosphoserine. | Swiss-Prot 53.0 |
| 311 | Phosphoserine | Phospho.ELM 6.0 |
| 315 | Phosphothreonine. | Swiss-Prot 53.0 |
| 315 | Phosphothreonine | Phospho.ELM 6.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 62 | Sulfotyrosine | HMM predict |
| 129 | O-linked | HMM predict |
| 129 | Phosphoserine(ATM) | HMM predict |
| 132 | Phosphoserine(IKK) | HMM predict |
| 133 | Phosphoserine(CDC2) | HMM predict |
| 133 | Phosphoserine(ATM) | HMM predict |
| 137 | O-linked | HMM predict |
| 139 | Phosphoserine(IKK) | HMM predict |
| 171 | Phosphothreonine(PKA) | HMM predict |
| 322 | Phosphotyrosine(INSR) | HMM predict |
| 322 | Phosphotyrosine(SRC) | HMM predict |
| 322 | Phosphotyrosine(Syk) | HMM predict |
| 329 | Phosphoserine(CK1) | HMM predict |
| 443 | Phosphoserine(ATM) | HMM predict |
- RefSeq ID: NM_002757
- Location:chr15 65622074-65886504
- strand:+
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| ETS1 | Jurkat | GSE17954 | 65621156 | 65622668 | 1512 | 163 |
| H3K4me3 | colorectal | cancer | 65620698 | 65620912 | 214 | 1270 |
| H3K4me3 | colorectal | cancer | 65621271 | 65621823 | 552 | 528 |
| H3ac | HepG2 | E | 65620628 | 65620912 | 284 | 1305 |
| H3ac | HepG2 | E | 65621271 | 65621725 | 454 | 577 |
| Myc | hES | GSE17917 | 65621840 | 65622117 | 277 | 96 |
| Nanog | hES | GSE18292 | 65602667 | 65603314 | 647 | 19084 |
| P300 | T30-glioblastoma | GSE21026 | 65621169 | 65622594 | 1425 | 193 |
| PHF8 | HeLa | GSE20725 | 65621422 | 65622677 | 1255 | 25 |
| TAF | Hela | GSE8489 | 65621271 | 65621996 | 725 | 441 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| hScc1 | Bcell | GSE12603 | 65888946 | 65889263 | 317 | 2600 |
| hScc1 | Bcell | GSE12603 | 65890719 | 65890964 | 245 | 4337 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CBP | Jurkat | GSE17954 | 65861735 | 65865783 | 4048 | 0 |
| CBP | T0-glioblastoma | GSE21026 | 65713695 | 65714246 | 551 | 0 |
| ER | E2-MCF7 | GSE14664 | 65646158 | 65646199 | 41 | 0 |
| ER | E2-MCF7 | GSE14664 | 65702236 | 65702271 | 35 | 0 |
| ER | Fulvestrant-MCF7 | GSE14664 | 65646157 | 65646199 | 42 | 0 |
| Fos | K562 | GSE19551 | 65629700 | 65630163 | 463 | 0 |
| H3ac | HepG2 | E | 65622479 | 65623085 | 606 | 0 |
| NRSF | mAb | Jurkat | 65707905 | 65708432 | 527 | 0 |
| Nanog | ES | GSE20650 | 65628236 | 65628675 | 439 | 0 |
| Nanog | hES | GSE18292 | 65710048 | 65710258 | 210 | 0 |
| Oct1 | H2O2-Hela | GSE14283 | 65646166 | 65646195 | 29 | 0 |
| Oct1 | H2O2-Hela | GSE14283 | 65795664 | 65795727 | 63 | 0 |
| Oct1 | Hela | GSE14283 | 65646158 | 65646199 | 41 | 0 |
| Oct1 | Hela | GSE14283 | 65676329 | 65676362 | 33 | 0 |
| Oct1 | Hela | GSE14283 | 65690434 | 65690462 | 28 | 0 |
| Oct1 | Hela | GSE14283 | 65866550 | 65866580 | 30 | 0 |
| Oct4 | hES | GSE21916 | 65870265 | 65870840 | 575 | 0 |
| P300 | T0-glioblastoma | GSE21026 | 65713689 | 65714129 | 440 | 0 |
| P300 | T30-glioblastoma | GSE21026 | 65793682 | 65794143 | 461 | 0 |
| PHF8 | 293T | GSE20725 | 65621728 | 65622938 | 1210 | 0 |
| Rb | Senescent | GSE19898 | 65621753 | 65622664 | 911 | 0 |
| hScc1 | Bcell | GSE12603 | 65621482 | 65622827 | 1345 | 0 |
| hScc1 | Bcell | GSE12603 | 65838980 | 65839127 | 147 | 0 |
| hScc1 | Bcell | GSE12603 | 65862490 | 65863106 | 616 | 0 |
| hScc1 | Bcell | GSE12603 | 65885793 | 65886205 | 412 | 0 |
| hScc1 | CdLS | GSE12603 | 65862562 | 65863106 | 544 | 0 |
Validated miRNA targets| Cluster ID | Plue Type | Plus Gene Name | Plus Chromosome | Plus Start | Plus End | Overlap Length | Minus Type | Minus Gene Name | Minus Chromosome | Minus Star | Minus End | Type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 8981 | mRNA | MAP2K5 | chr15 | 65622074 | 65886505 | 1762 | HTC | chr15 | 65685638 | 65687400 | Non-exonic Bidirectional (NOB) pairs | |