AutismKB 2.0

Annotation Detail for PRL


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Basic Information Top
Gene Symbol:PRL ( - )
Gene Full Name: prolactin
Band: 6p22.3
Quick LinksEntrez ID:5617; OMIM: 176760; Uniprot ID:PRL_HUMAN; ENSEMBL ID: ENSG00000172179; HGNC ID: 9445
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
59N-linked (GlcNAc...); partial.
Location(AA) Modifications Resource
59N-linked (GlcNAc...); partial.Swiss-Prot 53.0
163PhosphoserinePhospho.ELM 6.0
194PhosphoserinePhospho.ELM 6.0
207Phosphoserine (PAK2)Phospho.ELM 6.0
Location(AA) Modification Resource
6Phosphoserine(CDC2)HMM predict
93Phosphothreonine(MAPK)HMM predict
163Phosphoserine(ATM)HMM predict
221IsoleucineHMM predict
226AsparagineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000948
  • Location:chr6 22395458-22405708
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Nanog hESGSE18292 22424976 22425160 184 19360
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TAF HelaGSE8489 22388965 22389426 461 6263
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 HelaGSE14283 22398437 22398489 52 0
Oct1 HelaGSE14283 22399768 22399804 36 0
Validated miRNA targets Top
Cis-Nats regulation Top

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018