Annotation Detail for PROS1
Basic Information Top
| Gene Symbol: | PROS1 ( PROS,PS21,PS22,PS23,PS24,PS25,PSA ) |
|---|---|
| Gene Full Name: | protein S (alpha) |
| Band: | 3q11.1 |
| Quick Links | Entrez ID:5627; OMIM: 176880; Uniprot ID:PROS_HUMAN; ENSEMBL ID: ENSG00000184500; HGNC ID: 9456 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 47 | 4-carboxyglutamate. | |
| 48 | 4-carboxyglutamate. | |
| 55 | 4-carboxyglutamate. | |
| 57 | 4-carboxyglutamate. | |
| 60 | 4-carboxyglutamate. | |
| 61 | 4-carboxyglutamate. | |
| 66 | 4-carboxyglutamate. | |
| 67 | 4-carboxyglutamate. | |
| 70 | 4-carboxyglutamate. | |
| 73 | 4-carboxyglutamate. | |
| 77 | 4-carboxyglutamate. | |
| 136 | (3R)-3-hydroxyaspartate (By similarity). | |
| 499 | N-linked (GlcNAc...). | |
| 509 | N-linked (GlcNAc...) (Potential). | |
| 530 | N-linked (GlcNAc...). | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 47 | 4-carboxyglutamate. | Swiss-Prot 53.0 |
| 48 | 4-carboxyglutamate. | Swiss-Prot 53.0 |
| 55 | 4-carboxyglutamate. | Swiss-Prot 53.0 |
| 57 | 4-carboxyglutamate. | Swiss-Prot 53.0 |
| 60 | 4-carboxyglutamate. | Swiss-Prot 53.0 |
| 61 | 4-carboxyglutamate. | Swiss-Prot 53.0 |
| 66 | 4-carboxyglutamate. | Swiss-Prot 53.0 |
| 67 | 4-carboxyglutamate. | Swiss-Prot 53.0 |
| 70 | 4-carboxyglutamate. | Swiss-Prot 53.0 |
| 73 | 4-carboxyglutamate. | Swiss-Prot 53.0 |
| 77 | 4-carboxyglutamate. | Swiss-Prot 53.0 |
| 136 | 3-hydroxyaspartate (By similarity). | Swiss-Prot 53.0 |
| 499 | N-linked (GlcNAc...). | Swiss-Prot 53.0 |
| 509 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| 530 | N-linked (GlcNAc...). | Swiss-Prot 53.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 44 | Phosphoserine(PKG) | HMM predict |
| 80 | Sulfotyrosine | HMM predict |
| 131 | Phosphotyrosine(Jak) | HMM predict |
| 131 | Phosphotyrosine(INSR) | HMM predict |
| 210 | Phosphoserine(IKK) | HMM predict |
| 332 | Phosphotyrosine(INSR) | HMM predict |
| 499 | N-linked | HMM predict |
| 530 | N-linked | HMM predict |
| 531 | N-linked | HMM predict |
| 544 | Phosphoserine(CK1) | HMM predict |
| 544 | Phosphoserine(CK2) | HMM predict |
| 628 | O-linked | HMM predict |
| 656 | Phosphoserine(CK1) | HMM predict |
| 665 | Phosphoserine(IKK) | HMM predict |
- RefSeq ID: NM_000313
- Location:chr3 95074646-95175394
- strand:-
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| p130 | Quiescent | GSE19898 | 95175375 | 95175803 | 428 | 195 |
| p130 | Senescent | GSE19898 | 95175417 | 95175779 | 362 | 204 |
| p130 | shRbQuiescent | GSE19898 | 95175140 | 95175850 | 710 | 101 |
| p130 | shRbSenescent | GSE19898 | 95175426 | 95175853 | 427 | 245 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| ER | E2-MCF7 | GSE14664 | 95060350 | 95060441 | 91 | 14251 |
| Oct1 | H2O2-Hela | GSE14283 | 95057154 | 95057191 | 37 | 17474 |
| Oct1 | Hela | GSE14283 | 95057154 | 95057193 | 39 | 17473 |
| Oct1 | Hela | GSE14283 | 95065941 | 95065978 | 37 | 8687 |
| Oct1 | Hela | GSE14283 | 95068687 | 95068753 | 66 | 5927 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | G2 | GSE9613 | 95174959 | 95175570 | 611 | 0 |
| ER | E2-MCF7 | GSE14664 | 95096225 | 95096316 | 91 | 0 |
| ER | Fulvestrant-MCF7 | GSE14664 | 95100797 | 95100853 | 56 | 0 |
| ER | Fulvestrant-MCF7 | GSE14664 | 95159428 | 95159478 | 50 | 0 |
| Fos | K562 | GSE19551 | 95171432 | 95172019 | 587 | 0 |
| H3K4me2 | HCT116 | GSE10453 | 95174410 | 95175100 | 690 | 0 |
| H3K4me3 | colorectal | cancer | 95174588 | 95175604 | 1016 | 0 |
| H3ac | HepG2 | E | 95174410 | 95175100 | 690 | 0 |
| NRSF | mAb | Jurkat | 95088211 | 95088414 | 203 | 0 |
| Oct1 | H2O2-Hela | GSE14283 | 95076439 | 95076472 | 33 | 0 |
| Oct1 | H2O2-Hela | GSE14283 | 95088820 | 95088849 | 29 | 0 |
| Oct1 | H2O2-Hela | GSE14283 | 95141536 | 95141564 | 28 | 0 |
| Oct1 | Hela | GSE14283 | 95076433 | 95076476 | 43 | 0 |
| Oct1 | Hela | GSE14283 | 95088819 | 95088849 | 30 | 0 |
| Oct1 | Hela | GSE14283 | 95125533 | 95125568 | 35 | 0 |
| Oct1 | Hela | GSE14283 | 95146237 | 95146269 | 32 | 0 |
| Oct1 | Hela | GSE14283 | 95147272 | 95147298 | 26 | 0 |
| Oct1 | Hela | GSE14283 | 95171435 | 95171466 | 31 | 0 |
| P300 | T0-glioblastoma | GSE21026 | 95111450 | 95112159 | 709 | 0 |
| PHF8 | Hs68minusFBS | GSE20725 | 95174862 | 95175776 | 914 | 0 |
| STAT1 | IFN | SISSRdata | 95174681 | 95175953 | 1272 | 0 |
| TAF | Hela | GSE8489 | 95122060 | 95122271 | 211 | 0 |
| TAF | Hela | GSE8489 | 95133917 | 95134275 | 358 | 0 |
| TAF | k562 | GSE8489 | 95174410 | 95175958 | 1548 | 0 |
| TFAP2C | MCF7 | GSE21234 | 95151382 | 95151828 | 446 | 0 |
| hScc1 | G2 | GSE9613 | 95174959 | 95175528 | 569 | 0 |
| p63 | keratinocytes | GSE17611 | 95079705 | 95080529 | 824 | 0 |
Validated miRNA targets