AutismKB 2.0

Annotation Detail for RELN


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Basic Information Top
Gene Symbol:RELN ( PRO1598,RL )
Gene Full Name: reelin
Band: 7q22.1
Quick LinksEntrez ID:5649; OMIM: 600514; Uniprot ID:RELN_HUMAN; ENSEMBL ID: ENSG00000189056; HGNC ID: 9957
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
140N-linked (GlcNAc...) (Potential).
257N-linked (GlcNAc...) (Potential).
289N-linked (GlcNAc...) (Potential).
305N-linked (GlcNAc...).
628N-linked (GlcNAc...) (Potential).
1266N-linked (GlcNAc...) (Potential).
1599N-linked (GlcNAc...) (Potential).
1749N-linked (GlcNAc...) (Potential).
1920N-linked (GlcNAc...).
2144N-linked (GlcNAc...) (Potential).
2268N-linked (GlcNAc...) (Potential).
2316N-linked (GlcNAc...) (Potential).
2568N-linked (GlcNAc...) (Potential).
2961N-linked (GlcNAc...) (Potential).
3015N-linked (GlcNAc...).
3072N-linked (GlcNAc...) (Potential).
3184N-linked (GlcNAc...) (Potential).
3411N-linked (GlcNAc...) (Potential).
3438N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
140N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
257N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
289N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
305N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
628N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1266N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1599N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1749N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1920N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2144N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2268N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2316N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2568N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2961N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
3015N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
3072N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
3184N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
3411N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
3438N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
64N-linkedHMM predict
67Phosphotyrosine(SRC)HMM predict
80O-linkedHMM predict
101Phosphoserine(ATM)HMM predict
197Phosphoserine(CK1)HMM predict
257N-linkedHMM predict
258O-linkedHMM predict
267O-linkedHMM predict
278Phosphoserine(ATM)HMM predict
289N-linkedHMM predict
290N-linkedHMM predict
304Phosphoserine(IKK)HMM predict
379Phosphothreonine(PKC)HMM predict
426Phosphoserine(ATM)HMM predict
511O-linkedHMM predict
517Phosphotyrosine(Syk)HMM predict
533Phosphothreonine(MAPK)HMM predict
602Phosphoserine(IKK)HMM predict
621O-linkedHMM predict
628N-linkedHMM predict
629Phosphotyrosine(INSR)HMM predict
633N-linkedHMM predict
717Phosphoserine(CDK)HMM predict
721Phosphoserine(CK1)HMM predict
722Phosphoserine(PKB)HMM predict
765Phosphoserine(ATM)HMM predict
780Phosphoserine(IKK)HMM predict
847Phosphoserine(CDK)HMM predict
848Phosphoserine(ATM)HMM predict
1016Phosphotyrosine(Syk)HMM predict
1148PhosphoserineHMM predict
1174Phosphoserine(ATM)HMM predict
1192Phosphothreonine(MAPK)HMM predict
1209SulfotyrosineHMM predict
1209Phosphotyrosine(INSR)HMM predict
1232N-linkedHMM predict
1238N-linkedHMM predict
1240Phosphotyrosine(Syk)HMM predict
1266N-linkedHMM predict
1355Phosphoserine(IKK)HMM predict
1355Phosphoserine(CK1)HMM predict
1394Phosphoserine(ATM)HMM predict
1394Phosphoserine(CK1)HMM predict
1599N-linkedHMM predict
1602Phosphoserine(ATM)HMM predict
1717Phosphotyrosine(INSR)HMM predict
1738Phosphoserine(CDC2)HMM predict
1749N-linkedHMM predict
1861Phosphotyrosine(EGFR)HMM predict
1873Phosphothreonine(CDC2)HMM predict
1873Phosphothreonine(MAPK)HMM predict
1873Phosphothreonine(CDK)HMM predict
1879Phosphoserine(CK1)HMM predict
1879Phosphoserine(IKK)HMM predict
1887Phosphoserine(ATM)HMM predict
1899Phosphotyrosine(Jak)HMM predict
1920N-linkedHMM predict
2061Phosphoserine(CDK)HMM predict
2062Phosphoserine(CDK)HMM predict
2080Phosphotyrosine(Syk)HMM predict
2144N-linkedHMM predict
2162Phosphoserine(PKG)HMM predict
2268N-linkedHMM predict
2271N-linkedHMM predict
2389O-linkedHMM predict
2442Phosphothreonine(PKA)HMM predict
2513Phosphoserine(CK1)HMM predict
2528Phosphoserine(ATM)HMM predict
2568N-linkedHMM predict
2571N-linkedHMM predict
2675O-linkedHMM predict
2706Phosphoserine(CK1)HMM predict
2725Phosphoserine(CDC2)HMM predict
2748Phosphothreonine(MAPK)HMM predict
2805Phosphoserine(ATM)HMM predict
2805Phosphoserine(IKK)HMM predict
2961N-linkedHMM predict
3015N-linkedHMM predict
3054N-linkedHMM predict
3056Phosphoserine(ATM)HMM predict
3072N-linkedHMM predict
3078N-linkedHMM predict
3088N-linkedHMM predict
3149Phosphoserine(CK1)HMM predict
3180Phosphotyrosine(EGFR)HMM predict
3184N-linkedHMM predict
3185Phosphoserine(CK1)HMM predict
3201Phosphoserine(CK1)HMM predict
3259Phosphoserine(ATM)HMM predict
3340Phosphoserine(IKK)HMM predict
3340Phosphoserine(ATM)HMM predict
3344Phosphoserine(IKK)HMM predict
3347Phosphoserine(CK1)HMM predict
3411N-linkedHMM predict
3438N-linkedHMM predict
3455Phosphoserine(PKG)HMM predict
3459TyrosineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005045
  • Location:chr7 102899472-103417197
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 103417115 103417573 458 147
Gata1 K562GSE18868 103423665 103424355 690 6813
Gata2 K562GSE18868 103423668 103424383 715 6828
H3K4me3 colorectalcancer 103417198 103417474 276 139
Myc K562GSE19551 103423650 103424235 585 6745
USF1 HepG2E 103427501 103427676 175 10391
hScc1 BcellGSE12603 103417115 103417942 827 331
hScc1 CdLSGSE12603 103416987 103418127 1140 360
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 H2O2-HelaGSE14283 102897211 102897242 31 2246
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 102952067 102952450 383 0
CTCF G2GSE9613 103000938 103001615 677 0
CTCF G2GSE9613 103333684 103333881 197 0
ER E2-MCF7GSE14664 103136493 103136531 38 0
ER E2-MCF7GSE14664 103145538 103145573 35 0
ER E2-MCF7GSE14664 103186153 103186242 89 0
FOXA1 MCF7GSE15244 102915153 102915519 366 0
Fos K562GSE19551 103343624 103344206 582 0
FoxA1 MCF7MACSdata 102915110 102915492 382 0
FoxA1 MCF7MACSdata 103038281 103038511 230 0
FoxA1 MCF7MACSdata 103088137 103088494 357 0
Gata1 K562GSE18868 103271367 103271859 492 0
Gata2 K562GSE18868 103237931 103238568 637 0
Gata2 K562GSE18868 103271232 103271898 666 0
H3K27me3 colorectalcancer 103416171 103416743 572 0
Myc K562GSE19551 102951969 102952290 321 0
Myc K562GSE19551 103271300 103271876 576 0
NRSF JurkatGSE13047 103063793 103064274 481 0
NRSF JurkatGSE13047 103278534 103279788 1254 0
NRSF mAbJurkat 103062842 103064245 1403 0
NRSF mAbJurkat 103064499 103066094 1595 0
NRSF mAbJurkat 103266819 103267333 514 0
NRSF mAbJurkat 103271623 103272086 463 0
NRSF mAbJurkat 103272442 103272795 353 0
NRSF mAbJurkat 103275274 103277852 2578 0
NRSF mAbJurkat 103279194 103280893 1699 0
NRSF mAbJurkat 103282194 103283209 1015 0
NRSF mAbJurkat 103283676 103283951 275 0
NRSF-mono JurkatQuESTdata 103063792 103064273 481 0
NRSF-mono JurkatQuESTdata 103278955 103279765 810 0
NRSF pAbJurkat 103276090 103277333 1243 0
NRSF pAbJurkat 103279194 103279985 791 0
NRSF-poly JurkatQuESTdata 103063750 103064245 495 0
NRSF-poly JurkatQuESTdata 103278767 103279788 1021 0
Nanog ESGSE20650 103080893 103081401 508 0
Oct1 H2O2-HelaGSE14283 103096587 103096629 42 0
Oct1 H2O2-HelaGSE14283 103103394 103103427 33 0
Oct1 H2O2-HelaGSE14283 103141267 103141297 30 0
Oct1 H2O2-HelaGSE14283 103283206 103283237 31 0
Oct1 H2O2-HelaGSE14283 103328103 103328141 38 0
Oct1 HelaGSE14283 103096587 103096627 40 0
Oct1 HelaGSE14283 103136494 103136527 33 0
Oct1 HelaGSE14283 103145396 103145496 100 0
Oct1 HelaGSE14283 103328098 103328156 58 0
PAX3-FKHR Rh4GSE19063 103079283 103080360 1077 0
RNAII Tamoxifen-MCF7GSE14664 103265466 103265503 37 0
STAT1 HeLaGSE12783 103087783 103089136 1353 0
STAT1 IFNSISSRdata 103087912 103088936 1024 0
Sox2 hESGSE18292 102952164 102952314 150 0
TFAP2C MCF7GSE21234 102928874 102929166 292 0
USF1 HepG2E 103088121 103089135 1014 0
hScc1 BcellGSE12603 102952032 102952274 242 0
hScc1 BcellGSE12603 103001150 103001755 605 0
hScc1 CdLSGSE12603 102951777 102952412 635 0
hScc1 CdLSGSE12603 103000974 103001580 606 0
hScc1 G2GSE9613 103000938 103001615 677 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-128 hsa-mir-128-1 2 19713529
hsa-miR-128 hsa-mir-128-2 3 19713529
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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