Annotation Detail for PSEN2
Basic Information Top
| Gene Symbol: | PSEN2 ( AD3L,AD4,PS2,STM2 ) |
|---|---|
| Gene Full Name: | presenilin 2 (Alzheimer disease 4) |
| Band: | 1q42.13 |
| Quick Links | Entrez ID:5664; OMIM: 600759; Uniprot ID:PSN2_HUMAN; ENSEMBL ID: ENSG00000143801; HGNC ID: 9509 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 22 | Phosphoserine. | |
| 25 | Phosphoserine. | |
| 30 | Phosphoserine (By similarity). | |
| 416 | PAL. | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 7 | Phosphoserine (CK2 | |
| 9 | Phosphoserine (CK2 | |
| 19 | Phosphoserine (CK2 | |
| 327 | Phosphoserine (CK1 delta) | Phospho.ELM 6.0 |
| 330 | Phosphoserine (CK1 delta;CK) | Phospho.ELM 6.0 |
| 335 | Phosphoserine (CK2 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 25 | Phosphoserine(CDK) | HMM predict |
| 27 | O-linked | HMM predict |
| 27 | Phosphothreonine(MAPK) | HMM predict |
| 311 | Phosphoserine(ATM) | HMM predict |
| 328 | Phosphotyrosine(EGFR) | HMM predict |
| 328 | Phosphotyrosine(Syk) | HMM predict |
| 328 | Sulfotyrosine | HMM predict |
| 336 | Phosphotyrosine(EGFR) | HMM predict |
| 386 | N-linked | HMM predict |
- RefSeq ID: NM_000447
- Location:chr1 225125582-225150419
- strand:+
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| Nanog | ES | GSE20650 | 225117732 | 225118155 | 423 | 7639 |
| Nanog | hES | GSE18292 | 225117889 | 225118242 | 353 | 7517 |
| Rb | Growing | GSE19898 | 225124655 | 225124825 | 170 | 843 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | CD4 | GSE12889 | 225166951 | 225167190 | 239 | 16651 |
| CTCF | CD4 | SISSRdata | 225166951 | 225167190 | 239 | 16651 |
| hScc1 | CdLS | GSE12603 | 225166987 | 225167524 | 537 | 16836 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | G2 | GSE9613 | 225140802 | 225141102 | 300 | 0 |
| Fos | K562 | GSE19551 | 225130079 | 225130597 | 518 | 0 |
| H3K4me3 | colorectal | cancer | 225125795 | 225126076 | 281 | 0 |
| H3ac | HepG2 | E | 225125795 | 225126007 | 212 | 0 |
| TFAP2C | MCF7 | GSE21234 | 225130172 | 225130594 | 422 | 0 |
| hScc1 | Bcell | GSE12603 | 225144971 | 225145180 | 209 | 0 |
| p130 | Quiescent | GSE19898 | 225130022 | 225130200 | 178 | 0 |
Validated miRNA targets