AutismKB 2.0

Annotation Detail for KCNK12


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Basic Information Top
Gene Symbol:KCNK12 ( THIK-2,THIK2 )
Gene Full Name: potassium channel, subfamily K, member 12
Band: 2p16.3
Quick LinksEntrez ID:56660; OMIM: 607366; Uniprot ID:KCNKC_HUMAN; ENSEMBL ID: ENSG00000184261; HGNC ID: 6274
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
13Phosphoserine.
78N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
13Phosphoserine.Swiss-Prot 53.0
78N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
5Phosphoserine(CDK)HMM predict
5Phosphoserine(CDC2)HMM predict
5Phosphoserine(ATM)HMM predict
13Phosphoserine(PKA)HMM predict
26S-palmitoylHMM predict
27S-palmitoylHMM predict
198Phosphoserine(PKA)HMM predict
198Phosphoserine(PKG)HMM predict
205Phosphoserine(CK1)HMM predict
228Phosphoserine(IKK)HMM predict
289S-palmitoylHMM predict
290S-palmitoylHMM predict
336Phosphothreonine(MAPK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_022055
  • Location:chr2 47601420-47650973
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 47650374 47651603 1229 15
CTCF G2GSE9613 47652127 47652884 757 1532
H3K27me3 colorectalcancer 47652851 47654520 1669 2712
NRSF JurkatGSE13047 47651502 47652498 996 1027
NRSF JurkatSISSRdata 47651657 47652448 791 1079
NRSF mAbJurkat 47652957 47654520 1563 2765
NRSF mAbJurkat 47655906 47656859 953 5409
NRSF mAbJurkat 47658139 47658630 491 7411
NRSF-mono JurkatQuESTdata 47651346 47652781 1435 1090
NRSF-poly JurkatQuESTdata 47650949 47651257 308 130
NRSF-poly JurkatQuESTdata 47651313 47652822 1509 1094
hScc1 BcellGSE12603 47650614 47651339 725 3
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 47596685 47596717 32 4720
Oct1 HelaGSE14283 47591608 47591649 41 9792
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 47601943 47602238 295 0
CTCF CD4SISSRdata 47601943 47602238 295 0
CTCF G2GSE9613 47601501 47602535 1034 0
CTCF G2GSE9613 47606194 47606416 222 0
CTCF G2GSE9613 47607937 47608251 314 0
CTCF G2GSE9613 47610782 47611138 356 0
CTCF G2GSE9613 47614995 47616092 1097 0
CTCF G2GSE9613 47619968 47620237 269 0
CTCF G2GSE9613 47638941 47639153 212 0
CTCF G2GSE9613 47641439 47641698 259 0
CTCF G2GSE9613 47642031 47642249 218 0
CTCF G2GSE9613 47642988 47643214 226 0
Fos K562GSE19551 47614765 47615408 643 0
H3K27me3 colorectalcancer 47647256 47648242 986 0
H3K27me3 colorectalcancer 47648492 47650443 1951 0
H3K4me3 colorectalcancer 47650614 47651033 419 0
NRSF mAbJurkat 47647220 47648783 1563 0
NRSF mAbJurkat 47649223 47650540 1317 0
Oct1 H2O2-HelaGSE14283 47643362 47643403 41 0
Oct1 HelaGSE14283 47643364 47643404 40 0
P300 T30-glioblastomaGSE21026 47614644 47615480 836 0
hScc1 BcellGSE12603 47601432 47602651 1219 0
hScc1 BcellGSE12603 47638941 47639153 212 0
hScc1 CdLSGSE12603 47601501 47602608 1107 0
hScc1 G2GSE9613 47650336 47651603 1267 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
14257 EST chr2 47666556 47673989 7433 mRNA KCNK12 chr2 47659567 47709121 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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