AutismKB 2.0

Annotation Detail for PSMA3


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Basic Information Top
Gene Symbol:PSMA3 ( HC8,MGC12306,MGC32631,PSC3 )
Gene Full Name: proteasome (prosome, macropain) subunit, alpha type, 3
Band: 14q23.1
Quick LinksEntrez ID:5684; OMIM: 176843; Uniprot ID:PSA3_HUMAN; ENSEMBL ID: ENSG00000100567; HGNC ID: 9532
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylserine.
57N6-acetyllysine.
110N6-acetyllysine.
161Phosphotyrosine.
206N6-acetyllysine.
230N6-acetyllysine.
238N6-acetyllysine.
243Phosphoserine.
250Phosphoserine.
Location(AA) Modifications Resource
2N-acetylserine.Swiss-Prot 53.0
161Phosphotyrosine.Swiss-Prot 53.0
242Phosphoserine (CK2
243Phosphoserine (By similarity).Swiss-Prot 53.0
249Phosphoserine (CK2
250Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
16Phosphoserine(CDC2)HMM predict
239Phosphotyrosine(INSR)HMM predict
243Phosphoserine(PKG)HMM predict
250Phosphoserine(CK1)HMM predict
250Phosphoserine(ATM)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002788
  • Location:chr14 57781345-57808478
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 57776811 57777157 346 4362
PHF8 Hs68plusFBSGSE20725 57775801 57776926 1125 4982
Pol3 GM12878GSE19551 57776013 57777219 1206 4730
Pol3 K562GSE19551 57775940 57776820 880 4966
TAF k562GSE8489 57780350 57782149 1799 96
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER MCF7GSE19013 57783150 57783741 591 0
Fos K562GSE19551 57781004 57781925 921 0
H3ac HepG2E 57781118 57782834 1716 0
H3ac HepG2E 57783201 57783592 391 0
Oct1 HelaGSE14283 57806317 57806353 36 0
RARA MCF7GSE15244 57781419 57782042 623 0
RARG MCF7GSE15244 57781243 57781933 690 0
TAF HelaGSE8489 57780350 57782799 2449 0
TAF k562GSE8489 57782580 57782834 254 0
p130 QuiescentGSE19898 57781194 57781754 560 0
p130 SenescentGSE19898 57780983 57781740 757 0
p130 shRbQuiescentGSE19898 57781042 57781858 816 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
7969 mRNA PSMA3 chr14 57781345 57808479 37 HTC chr14 57802435 57803981Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018