AutismKB 2.0

Annotation Detail for SPIRE1


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Basic Information Top
Gene Symbol:SPIRE1 ( MGC150621,MGC150622,Spir-1 )
Gene Full Name: spire homolog 1 (Drosophila)
Band: 18p11.21
Quick LinksEntrez ID:56907; OMIM: 609216; Uniprot ID:SPIR1_HUMAN; ENSEMBL ID: ENSG00000134278; HGNC ID: 30622
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
464Phosphoserine.
465Phosphoserine.
467Phosphoserine.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_020148
  • Location:chr18 12436511-12647911
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 12649954 12650166 212 2149
CTCF CD4SISSRdata 12649954 12650166 212 2149
CTCF G2GSE9613 12649695 12650084 389 1978
PHF8 293TGSE20725 12647729 12648792 1063 349
PHF8 HeLaGSE20725 12646910 12649080 2170 84
TFAP2C MCF7GSE21234 12648488 12648903 415 784
hScc1 BcellGSE12603 12648568 12648792 224 769
hScc1 BcellGSE12603 12649729 12650285 556 2096
hScc1 CdLSGSE12603 12649695 12650285 590 2079
hScc1 G2GSE9613 12649695 12650179 484 2026
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
p130 shRbSenescentGSE19898 12433065 12433238 173 3360
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF HelaGSE12889 12529982 12530164 182 0
CTCF G2GSE9613 12647454 12648081 627 0
ER E2-MCF7GSE14664 12476473 12476515 42 0
FOXA1 MCF7GSE15244 12564261 12565224 963 0
FOXA1 MCF7GSE15244 12630241 12630997 756 0
FOXA1 eGFPGSE10845 12564261 12565224 963 0
FOXA1 eGFPGSE10845 12630241 12630997 756 0
Fos K562GSE19551 12611749 12612242 493 0
FoxA1 MCF7MACSdata 12564888 12565079 191 0
H3K4me3 colorectalcancer 12646714 12646930 216 0
H3ac HepG2E 12646608 12647138 530 0
Jun K562GSE19551 12611944 12612221 277 0
KLF4 hESGSE17917 12460628 12460943 315 0
Myc K562GSE19551 12622076 12622486 410 0
Myc K562GSE19551 12630650 12631108 458 0
Nanog ESGSE20650 12637806 12638263 457 0
Oct1 H2O2-HelaGSE14283 12484593 12484632 39 0
Oct1 H2O2-HelaGSE14283 12578582 12578617 35 0
Oct1 HelaGSE14283 12447212 12447268 56 0
Oct1 HelaGSE14283 12484593 12484632 39 0
Oct1 HelaGSE14283 12578581 12578618 37 0
Oct1 HelaGSE14283 12580634 12580669 35 0
Oct1 HelaGSE14283 12592064 12592092 28 0
Oct1 HelaGSE14283 12617259 12617289 30 0
Oct4 hESGSE21916 12637824 12638190 366 0
P300 T30-glioblastomaGSE21026 12596747 12597831 1084 0
Rb shRbSenescenceGSE19898 12642919 12643156 237 0
Sox2 hESGSE18292 12641735 12642111 376 0
Stat6 IL-4-hr4GSE17850 12450919 12451426 507 0
TAF HelaGSE8489 12600384 12601149 765 0
TFAP2C MCF7GSE21234 12521829 12522243 414 0
TFAP2C MCF7GSE21234 12587643 12588088 445 0
TFAP2C MCF7GSE21234 12635393 12636215 822 0
hScc1 BcellGSE12603 12647040 12648081 1041 0
p130 QuiescentGSE19898 12593428 12593585 157 0
p130 QuiescentGSE19898 12646874 12647041 167 0
p63 keratinocytesGSE17611 12460443 12461304 861 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
11953 mRNA SPIRE1 chr18 12435249 12437789 1278 mRNA SPIRE1 chr18 12436511 12536905Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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