AutismKB 2.0

Annotation Detail for C21orf7


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Basic Information Top
Gene Symbol:C21orf7 ( HC21ORF7,TAK1L,TAKL,TAKL-1,TAKL-2,TAKL-4 )
Gene Full Name: chromosome 21 open reading frame 7
Band: 21q22.3
Quick LinksEntrez ID:56911; OMIM: 611110; Uniprot ID:TAK1L_HUMAN; ENSEMBL ID: ENSG00000156265; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
63Phosphoserine(ATM)HMM predict
121O-linkedHMM predict
126Phosphothreonine(MAPK)HMM predict
126Phosphothreonine(CDK)HMM predict
155PhosphoserineHMM predict
214N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_020152
  • Location:chr21 29374743-29470070
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K4me3 colorectalcancer 29371899 29372120 221 2734
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 29475714 29477608 1894 6591
P300 T30-glioblastomaGSE21026 29475709 29477769 2060 6669
PolII HeLaGSE12783 29475591 29477701 2110 6576
STAT1 HeLaGSE12782 29475574 29478354 2780 6894
STAT1 HeLaGSE12783 29475595 29477806 2211 6630
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 29408562 29410192 1630 0
CTCF CD4GSE12889 29384224 29384466 242 0
CTCF CD4GSE12889 29458644 29458778 134 0
CTCF CD4SISSRdata 29384224 29384466 242 0
CTCF CD4SISSRdata 29458644 29458778 134 0
FOXA1 MCF7GSE15244 29469555 29470147 592 0
FoxA1 MCF7MACSdata 29469626 29469863 237 0
NFkBII GM12878GSE19485 29398037 29399178 1141 0
Nanog ESGSE20650 29379881 29380360 479 0
Nanog hESGSE18292 29379954 29380152 198 0
Nanog hESGSE18292 29458679 29458835 156 0
P300 T30-glioblastomaGSE21026 29408652 29409751 1099 0
P300 T30-glioblastomaGSE21026 29423917 29425754 1837 0
P300 T30-glioblastomaGSE21026 29438708 29440293 1585 0
Sox2 hESGSE18292 29384282 29384500 218 0
TFAP2C MCF7GSE21234 29434135 29434468 333 0
hScc1 CdLSGSE12603 29384288 29384535 247 0
p130 shRbQuiescentGSE19898 29424885 29425571 686 0
p63 keratinocytesGSE17611 29439416 29440791 1375 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018