AutismKB 2.0

Annotation Detail for PSMB4


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Basic Information Top
Gene Symbol:PSMB4 ( HN3,HsN3,PROS-26,PROS26 )
Gene Full Name: proteasome (prosome, macropain) subunit, beta type, 4
Band: 1q21.3
Quick LinksEntrez ID:5692; OMIM: 602177; Uniprot ID:PSB4_HUMAN; ENSEMBL ID: ENSG00000159377; HGNC ID: 9541
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
102Phosphotyrosine.
Location(AA) Modifications Resource
102Phosphotyrosine.Swiss-Prot 53.0
102PhosphotyrosinePhospho.ELM 6.0
Location(AA) Modification Resource
26Phosphoserine(PKB)HMM predict
92N-linkedHMM predict
102Phosphotyrosine(Syk)HMM predict
169Phosphotyrosine(INSR)HMM predict
206Phosphoserine(CK1)HMM predict
249SerineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002796
  • Location:chr1 149638664-149641035
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 149638415 149638666 251 124
CTCF CD4SISSRdata 149638415 149638666 251 124
Myc K562GSE19551 149638289 149638875 586 83
Nanog hESGSE18292 149638563 149638733 170 17
P300 T0-glioblastomaGSE21026 149638059 149639080 1021 95
hScc1 BcellGSE12603 149638373 149638809 436 74
hScc1 CdLSGSE12603 149638373 149638926 553 15
p130 QuiescentGSE19898 149638421 149638854 433 27
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 149638250 149639229 979 0
FOXA1 MCF7GSE15244 149638373 149639976 1603 0
GABP k562GSE8489 149638373 149640327 1954 0
H3K4me3 colorectalcancer 149638997 149639914 917 0
H3ac HepG2E 149638373 149640863 2490 0
P300 T30-glioblastomaGSE21026 149638154 149639699 1545 0
RARA MCF7GSE15244 149638373 149639942 1569 0
RARG MCF7GSE15244 149638373 149639976 1603 0
TAF k562GSE8489 149639136 149640398 1262 0
TAFII hESGSE17917 149638399 149638997 598 0
p130 SenescentGSE19898 149638366 149639231 865 0
p130 shRbQuiescentGSE19898 149638369 149639176 807 0
p130 shRbSenescentGSE19898 149638379 149639029 650 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018