AutismKB 2.0

Annotation Detail for PARP6


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Basic Information Top
Gene Symbol:PARP6 ( MGC131971,pART17 )
Gene Full Name: poly (ADP-ribose) polymerase family, member 6
Band: 15q23
Quick LinksEntrez ID:56965; OMIM: NA; Uniprot ID:PARP6_HUMAN; ENSEMBL ID: ENSG00000137817; HGNC ID: 26921
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
29Phosphoserine(IKK)HMM predict
103Phosphoserine(ATM)HMM predict
139Phosphoserine(ATM)HMM predict
183Phosphoserine(CDK)HMM predict
183Phosphoserine(CDC2)HMM predict
210N-linkedHMM predict
230Phosphoserine(CDC2)HMM predict
230Phosphoserine(ATM)HMM predict
230Phosphoserine(MAPK)HMM predict
250Phosphoserine(CDK)HMM predict
250Phosphoserine(MAPK)HMM predict
250O-linkedHMM predict
281Phosphothreonine(PKC)HMM predict
297N-linkedHMM predict
330Phosphothreonine(CK2)HMM predict
379Phosphotyrosine(INSR)HMM predict
451Phosphoserine(MAPK)HMM predict
451Phosphoserine(CDC2)HMM predict
490N-linkedHMM predict
508Phosphotyrosine(EGFR)HMM predict
508Phosphotyrosine(INSR)HMM predict
510Phosphoserine(CDC2)HMM predict
519Phosphotyrosine(Jak)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_020214
  • Location:chr15 70320576-70350681
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 70352166 70352515 349 1659
CTCF CD4SISSRdata 70352166 70352515 349 1659
CTCF G2GSE9613 70351605 70352483 878 1363
ETS1 JurkatGSE17954 70351619 70352751 1132 1504
H3K4me3 colorectalcancer 70351127 70351440 313 602
Myc hESGSE17917 70351854 70352276 422 1384
PHF8 293TGSE20725 70351350 70352585 1235 1286
PHF8 HeLaGSE20725 70351136 70352783 1647 1278
PHF8 Hs68minusFBSGSE20725 70351270 70352636 1366 1272
PHF8 Hs68plusFBSGSE20725 70351003 70352865 1862 1253
hScc1 BcellGSE12603 70351570 70352095 525 1151
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 70316466 70317509 1043 3589
CTCF G2GSE9613 70316859 70317019 160 3638
Fos K562GSE19551 70316652 70317300 648 3601
P300 T30-glioblastomaGSE21026 70316124 70317513 1389 3758
Rb QuiescentGSE19898 70316951 70317223 272 3490
TAF HelaGSE8489 70315748 70317382 1634 4012
p130 QuiescentGSE19898 70316684 70317120 436 3675
p130 SenescentGSE19898 70316563 70317216 653 3687
p130 SenescentGSE19898 70317295 70317621 326 3119
p130 shRbSenescentGSE19898 70316392 70317134 742 3814
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Nanog hESGSE18292 70322029 70322619 590 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018