AutismKB 2.0

Annotation Detail for PSMC1


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Basic Information Top
Gene Symbol:PSMC1 ( MGC24583,MGC8541,P26S4,S4,p56 )
Gene Full Name: proteasome (prosome, macropain) 26S subunit, ATPase, 1
Band: 14q32.11
Quick LinksEntrez ID:5700; OMIM: 602706; Uniprot ID:PRS4_HUMAN; ENSEMBL ID: ENSG00000100764; HGNC ID: 9547
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
4Phosphoserine.
258N6-acetyllysine.
439Phosphotyrosine.
Location(AA) Modifications Resource
2N-myristoyl glycine.Swiss-Prot 53.0
439Phosphotyrosine.Swiss-Prot 53.0
439PhosphotyrosinePhospho.ELM 6.0
Location(AA) Modification Resource
6Phosphoserine(ATM)HMM predict
25Phosphotyrosine(INSR)HMM predict
97Phosphoserine(CK1)HMM predict
172Phosphothreonine(PKC)HMM predict
184Phosphotyrosine(Syk)HMM predict
210SulfotyrosineHMM predict
211Phosphotyrosine(Syk)HMM predict
241N-linkedHMM predict
336Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002802
  • Location:chr14 89792646-89808716
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
GABP HelaGSE8489 89791246 89792712 1466 668
GABP k562GSE8489 89791282 89792675 1393 668
Myc K562GSE19551 89792379 89792849 470 33
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 89808407 89808446 39 0
ER Fulvestrant-MCF7GSE14664 89808409 89808446 37 0
ETS1 JurkatGSE17954 89792251 89793282 1031 0
GABP k562GSE8489 89793035 89793666 631 0
H3K4me3 colorectalcancer 89793035 89793666 631 0
H3ac HepG2E 89793035 89793666 631 0
Nanog ESGSE20650 89792507 89792824 317 0
Oct1 HelaGSE14283 89808408 89808447 39 0
P300 T0-glioblastomaGSE21026 89792475 89792920 445 0
P300 T30-glioblastomaGSE21026 89792433 89793069 636 0
PHF8 HeLaGSE20725 89792424 89793268 844 0
Rb QuiescentGSE19898 89792536 89792774 238 0
TAF HelaGSE8489 89792998 89793666 668 0
TAF k562GSE8489 89792998 89793491 493 0
TAFII hESGSE17917 89792382 89792988 606 0
p130 QuiescentGSE19898 89792937 89793284 347 0
p130 SenescentGSE19898 89792513 89792992 479 0
p130 SenescentGSE19898 89793021 89793230 209 0
p130 shRbQuiescentGSE19898 89792570 89793357 787 0
p130 shRbSenescentGSE19898 89793037 89793218 181 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018