AutismKB 2.0

Annotation Detail for TWSG1


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Basic Information Top
Gene Symbol:TWSG1 ( TSG )
Gene Full Name: twisted gastrulation homolog 1 (Drosophila)
Band: 18p11.22
Quick LinksEntrez ID:57045; OMIM: 605049; Uniprot ID:TWSG1_HUMAN; ENSEMBL ID: ENSG00000128791; HGNC ID: 12429
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
52N-linked (GlcNAc...) (Potential).
81N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
52N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
81N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
52N-linkedHMM predict
81N-linkedHMM predict
82Phosphotyrosine(Abl)HMM predict
85Phosphothreonine(MAPK)HMM predict
89O-linkedHMM predict
92Phosphothreonine(PKC)HMM predict
128Phosphoserine(CK1)HMM predict
147N-linkedHMM predict
153N-linkedHMM predict
161Phosphoserine(CK2)HMM predict
161Phosphoserine(ATM)HMM predict
205GlycineHMM predict
206ProlineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_020648
  • Location:chr18 9324850-9392416
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 9324506 9324832 326 182
CTCF CD4SISSRdata 9324506 9324832 326 182
FoxA1 MCF7MACSdata 9319551 9319767 216 5192
Myc K562GSE19551 9310987 9311403 416 13656
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
hScc1 BcellGSE12603 9393713 9394006 293 1443
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Nanog ESGSE20650 9370682 9371473 791 0
Oct1 H2O2-HelaGSE14283 9329957 9329985 28 0
Oct1 H2O2-HelaGSE14283 9366273 9366306 33 0
Oct1 HelaGSE14283 9366270 9366313 43 0
Oct1 HelaGSE14283 9380196 9380228 32 0
Oct4 ESGSE20650 9356216 9356598 382 0
PHF8 HeLaGSE20725 9324471 9325466 995 0
hScc1 BcellGSE12603 9324761 9325534 773 0
p130 shRbSenescentGSE19898 9327923 9328244 321 0
p63 keratinocytesGSE17611 9390246 9390874 628 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018