AutismKB 2.0

Annotation Detail for AVEN


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Basic Information Top
Gene Symbol:AVEN ( PDCD12 )
Gene Full Name: apoptosis, caspase activation inhibitor
Band: 15q14
Quick LinksEntrez ID:57099; OMIM: 605265; Uniprot ID:AVEN_HUMAN; ENSEMBL ID: ENSG00000169857; HGNC ID: 13509
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
94Phosphoserine.
Location(AA) Modifications Resource
94Phosphoserine (By similarity).Swiss-Prot 53.0
94PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
17MethylarginineHMM predict
37MethylarginineHMM predict
66MethylarginineHMM predict
75O-linkedHMM predict
99Phosphotyrosine(INSR)HMM predict
108N-linkedHMM predict
121Phosphotyrosine(EGFR)HMM predict
130N-linkedHMM predict
132Phosphoserine(CK2)HMM predict
135Phosphoserine(ATM)HMM predict
153Phosphoserine(ATM)HMM predict
177Phosphotyrosine(EGFR)HMM predict
219Phosphothreonine(CK2)HMM predict
259N-linkedHMM predict
261Phosphoserine(CDC2)HMM predict
268Phosphoserine(IKK)HMM predict
273Phosphoserine(IKK)HMM predict
273Phosphoserine(CDC2)HMM predict
273Phosphoserine(MAPK)HMM predict
313Phosphoserine(CK1)HMM predict
347N-linkedHMM predict
349Phosphothreonine(CK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_020371
  • Location:chr15 31945720-32118594
  • strand:-
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 32010680 32011184 504 0
ER E2-MCF7GSE14664 31967470 31967502 32 0
FOXA1 eGFPGSE10845 31945507 31946168 661 0
FoxA1 MCF7MACSdata 31945554 31945989 435 0
Nanog ESGSE20650 31987766 31988024 258 0
Nanog hESGSE18292 32086042 32086479 437 0
Oct1 H2O2-HelaGSE14283 31978961 31979011 50 0
Oct1 HelaGSE14283 31978962 31979009 47 0
Oct1 HelaGSE14283 32085131 32085197 66 0
TFAP2C MCF7GSE21234 31945532 31946211 679 0
TFAP2C MCF7GSE21234 32067313 32067740 427 0
TFAP2C MCF7GSE21234 32067945 32068233 288 0
hScc1 BcellGSE12603 32043535 32043786 251 0
hScc1 CdLSGSE12603 32043437 32044045 608 0
p63 keratinocytesGSE17611 32080944 32081474 530 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
8611 mRNA CHRM5 chr15 32097719 32144579 20876 mRNA AVEN chr15 31945720 32118595 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018