AutismKB 2.0

Annotation Detail for SMURF1


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Basic Information Top
Gene Symbol:SMURF1 ( KIAA1625 )
Gene Full Name: SMAD specific E3 ubiquitin protein ligase 1
Band: 7q22.1
Quick LinksEntrez ID:57154; OMIM: 605568; Uniprot ID:SMUF1_HUMAN; ENSEMBL ID: ENSG00000198742; HGNC ID: 16807
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
9N-linkedHMM predict
11Phosphoserine(PKC)HMM predict
50Phosphoserine(IKK)HMM predict
75Phosphoserine(IKK)HMM predict
75O-linkedHMM predict
113Phosphotyrosine(INSR)HMM predict
122N-linkedHMM predict
139Phosphothreonine(PKC)HMM predict
145Phosphothreonine(PKC)HMM predict
186O-linkedHMM predict
223Phosphothreonine(MAPK)HMM predict
223Phosphothreonine(CDC2)HMM predict
240Phosphotyrosine(Syk)HMM predict
269Phosphoserine(CDK)HMM predict
269Phosphoserine(CDC2)HMM predict
269Phosphoserine(IKK)HMM predict
271O-linkedHMM predict
329N-linkedHMM predict
353Phosphoserine(ATM)HMM predict
363Phosphoserine(CK1)HMM predict
413Phosphotyrosine(EGFR)HMM predict
440Phosphotyrosine(INSR)HMM predict
460SulfotyrosineHMM predict
471Phosphotyrosine(INSR)HMM predict
587Phosphotyrosine(INSR)HMM predict
587Phosphotyrosine(EGFR)HMM predict
737Phosphotyrosine(Syk)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_020429
  • Location:chr7 98462999-98579658
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FoxA1 MCF7MACSdata 98590925 98591145 220 11377
FoxA1 MCF7MACSdata 98598119 98598335 216 18569
Nanog hESGSE18292 98598132 98598299 167 18557
P300 T0-glioblastomaGSE21026 98597945 98598690 745 18659
PHF8 293TGSE20725 98579268 98580457 1189 204
RARA MCF7GSE15244 98597919 98598429 510 18516
Sox2 hESGSE18292 98598113 98598458 345 18627
Stat6 IL-4-hr4GSE17850 98579848 98580210 362 371
hScc1 G2GSE9613 98579295 98580337 1042 158
p130 QuiescentGSE19898 98579857 98580002 145 271
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 H2O2-HelaGSE14283 98457094 98457162 68 5872
Oct1 H2O2-HelaGSE14283 98462624 98462652 28 362
Oct1 HelaGSE14283 98457074 98457169 95 5878
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 98475922 98476246 324 0
CTCF CD4SISSRdata 98475922 98476246 324 0
CTCF HelaGSE12889 98476010 98476296 286 0
CTCF G2GSE9613 98463787 98464140 353 0
CTCF G2GSE9613 98469526 98470417 891 0
CTCF G2GSE9613 98472073 98472619 546 0
CTCF G2GSE9613 98473573 98474181 608 0
CTCF G2GSE9613 98475659 98476328 669 0
CTCF G2GSE9613 98479207 98479592 385 0
CTCF G2GSE9613 98514574 98515026 452 0
CTCF G2GSE9613 98577569 98577975 406 0
CTCF G2GSE9613 98579295 98579986 691 0
ER E2-MCF7GSE14664 98496337 98496370 33 0
ER E2-MCF7GSE14664 98529933 98530035 102 0
ER Fulvestrant-MCF7GSE14664 98468541 98468575 34 0
ER Fulvestrant-MCF7GSE14664 98497265 98497299 34 0
ER Fulvestrant-MCF7GSE14664 98515020 98515092 72 0
FOXA1 MCF7GSE15244 98563972 98564516 544 0
Fos K562GSE19551 98508368 98508886 518 0
Gata2 K562GSE18868 98522965 98523439 474 0
KLF4 hESGSE17917 98514740 98514910 170 0
Myc K562GSE19551 98475921 98476626 705 0
Myc K562GSE19551 98508457 98508728 271 0
Oct1 H2O2-HelaGSE14283 98540543 98540580 37 0
Oct1 H2O2-HelaGSE14283 98567712 98567743 31 0
Oct1 HelaGSE14283 98496342 98496374 32 0
Oct1 HelaGSE14283 98497264 98497298 34 0
Oct1 HelaGSE14283 98539529 98539559 30 0
Oct1 HelaGSE14283 98540543 98540579 36 0
PHF8 HeLaGSE20725 98578827 98580475 1648 0
Rb GrowingGSE19898 98578548 98578797 249 0
Rb SenescentGSE19898 98568537 98568968 431 0
Rb shRbQuiescentGSE19898 98577532 98577788 256 0
Rb shRbSenescenceGSE19898 98568570 98568784 214 0
TAF HelaGSE8489 98506329 98506468 139 0
TAF HelaGSE8489 98575383 98575620 237 0
TAF HelaGSE8489 98576368 98577310 942 0
TAFII hESGSE17917 98476021 98476341 320 0
TFAP2C MCF7GSE21234 98534406 98534930 524 0
TFAP2C MCF7GSE21234 98544675 98545345 670 0
hScc1 BcellGSE12603 98475899 98476328 429 0
hScc1 BcellGSE12603 98579295 98579794 499 0
hScc1 CdLSGSE12603 98475659 98476328 669 0
hScc1 G2GSE9613 98475587 98476328 741 0
p130 QuiescentGSE19898 98578407 98578623 216 0
p130 shRbSenescentGSE19898 98568540 98568857 317 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
24362 HTC chr7 98275212 98278751 205 mRNA SMURF1 chr7 98269714 98386374Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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