AutismKB 2.0

Annotation Detail for PTGER4


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Basic Information Top
Gene Symbol:PTGER4 ( EP4,EP4R,MGC126583 )
Gene Full Name: prostaglandin E receptor 4 (subtype EP4)
Band: 5p13.1
Quick LinksEntrez ID:5734; OMIM: 601586; Uniprot ID:PE2R4_HUMAN; ENSEMBL ID: ENSG00000171522; HGNC ID: 9596
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
7N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
7N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
222Phosphoserine (PKA
259Phosphoserine (PKA
354Phosphoserine (PKC
374PhosphoserinePhospho.ELM 6.0
377PhosphoserinePhospho.ELM 6.0
379PhosphoserinePhospho.ELM 6.0
382PhosphoserinePhospho.ELM 6.0
430Phosphoserine (PKC
433Phosphothreonine (PKC
460Phosphoserine (PKC
484Phosphoserine (PKC
Location(AA) Modification Resource
7N-linkedHMM predict
13Phosphoserine(CDC2)HMM predict
13Phosphoserine(CDK)HMM predict
19Phosphoserine(CDC2)HMM predict
177N-linkedHMM predict
184SulfotyrosineHMM predict
222Phosphoserine(PKA)HMM predict
222Phosphoserine(PKG)HMM predict
259Phosphoserine(PKC)HMM predict
307Phosphoserine(PKG)HMM predict
389Phosphoserine(CK1)HMM predict
390Phosphoserine(CK1)HMM predict
433Phosphothreonine(PKC)HMM predict
440Phosphoserine(CK1)HMM predict
442Phosphoserine(CK1)HMM predict
443Phosphoserine(ATM)HMM predict
450Phosphoserine(CK1)HMM predict
462MethylarginineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000958
  • Location:chr5 40715788-40729591
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 40715069 40715986 917 261
PHF8 HeLaGSE20725 40714328 40716553 2225 348
TAF HelaGSE8489 40714395 40714930 535 1126
TFAP2C MCF7GSE21234 40714921 40715692 771 482
hScc1 BcellGSE12603 40714963 40716159 1196 228
hScc1 G2GSE9613 40714725 40715986 1261 433
p63 keratinocytesGSE17611 40710257 40711230 973 5045
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TAF HelaGSE8489 40732250 40732623 373 2845
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 40725055 40725781 726 0
CTCF CD4GSE12889 40723993 40724294 301 0
CTCF CD4SISSRdata 40723993 40724294 301 0
CTCF G2GSE9613 40717327 40717616 289 0
CTCF G2GSE9613 40723870 40724532 662 0
CTCF G2GSE9613 40727832 40727979 147 0
Fos K562GSE19551 40725360 40725708 348 0
H3K4me3 colorectalcancer 40715950 40717287 1337 0
H3K4me3 colorectalcancer 40717919 40718689 770 0
P300 T30-glioblastomaGSE21026 40725066 40726003 937 0
hScc1 BcellGSE12603 40716532 40718073 1541 0
hScc1 BcellGSE12603 40723906 40724532 626 0
hScc1 CdLSGSE12603 40723653 40724567 914 0
hScc1 G2GSE9613 40723653 40724704 1051 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-16 hsa-mir-16-1 13 21081469
hsa-miR-16 hsa-mir-16-2 3 21081469
hsa-miR-21 hsa-mir-21 17 21081469
hsa-miR-21* hsa-mir-21 17 21081469
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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